Lycopene for High Blood Pressure (Hypertension)

Meta-analysis of 6 RCTs: systolic -5.6 mmHg. Improved endothelial function. Cooking with oil enhances absorption 2-3x. Strong observational associations with lower MI risk.

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The Bottom Line

Meta-analysis of 6 RCTs: systolic -5.6 mmHg. Improved endothelial function. Cooking with oil enhances absorption 2-3x. Strong observational associations with lower MI risk.

Key Statistics

Studies

400

Participants

↑

Positive

Grade

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Commonly Used Dosages

general:: 6-15 mg/day
cardiovascularsupport:: 15-30 mg/day

Upper limit: Not formally established; up to 75 mg/day used in clinical trials

Best taken: With meals containing fat (cooking with olive oil enhances absorption 2-3x)

Safety & Side Effects

Reported Side Effects

⚠ Generally well-tolerated
⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible

Known Interactions

● Blood pressure medications (may have mild additive effect)
● Beta-carotene (may compete for absorption)

Tolerable upper intake: Not formally established; up to 75 mg/day used in clinical trials

Always consult your healthcare provider before starting any supplement.

Frequently Asked Questions

Does Lycopene help with High Blood Pressure (Hypertension)?

Based on 6 studies with 400 participants, there is moderate evidence from clinical studies that Lycopene may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

How much Lycopene should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 6-15 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lycopene?

Reported side effects may include Generally well-tolerated, Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lycopene and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Related Evidence

Other ingredients for High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Magnesium B Potassium B Quercetin B Grape Seed Extract B

Lycopene for other conditions

Atherosclerosis D

Quick Verdict

Meta-analysis of 6 RCTs: systolic -5.6 mmHg. Improved endothelial function. Cooking with oil enhances absorption 2-3x. Strong observational associations with lower MI risk.

Evidence Strength72%

High confidence

Study Breakdown

RCT (0)Meta (0)Other (6)

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FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.