Olive Leaf ExtractOlive Leaf Extract
other
别名: Olea europaea Extract, Oleuropein, Hydroxytyrosol, EFLA 943, Benolea
About
Olive leaf extract contains oleuropein and hydroxytyrosol — the most potent natural antioxidant measured by ORAC — with ACE-inhibitory activity. A landmark 2011 RCT (148 hypertensive patients) found olive leaf extract at 500 mg BID reduced systolic blood pressure by 11.5 mmHg — comparable to captopril. EFSA has approved a health claim for olive oil polyphenols protecting LDL from oxidation.
How It Works
Oleuropein inhibits ACE activity reducing angiotensin II-mediated vasoconstriction; enhances endothelial nitric oxide production; potent antioxidant activity protects LDL from oxidation (hydroxytyrosol is the most potent natural antioxidant by ORAC); anti-inflammatory via NF-kB and COX-2 inhibition; improves arterial elasticity.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| High Blood Pressure (Hypertension) | B | 5 | 500 | 查看 → |
| Atherosclerosis | D | 2 | 100 | 查看 → |
Side Effects
- Generally well-tolerated
- Mild gastrointestinal discomfort
- Dizziness (if blood pressure drops significantly)
- Headache (rare)
Drug & Supplement Interactions
- Antihypertensives (additive blood pressure lowering — monitor BP)
- Diabetes medications (may lower blood sugar)
- Anticoagulants (mild theoretical interaction)
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Related Ingredients
FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。