Nitric Oxide BoostersNitric Oxide Boosters
other
别名: NO Boosters, Nitric Oxide Support, Endothelial Support, Neo40, Berkeley Life
About
Nitric oxide booster supplements combine L-arginine and L-citrulline to provide both immediate and sustained nitric oxide production for vascular support. A 2022 study showed the combination improved flow-mediated dilation more than either amino acid alone. Most evidence is extrapolated from individual component trials.
How It Works
Combination providing both substrate (L-arginine) and sustained precursor (L-citrulline) for endothelial nitric oxide synthase (eNOS); NO activates soluble guanylate cyclase causing vasodilation; combined arginine + citrulline provides immediate + sustained NO production; often formulated with cofactors that recycle oxidized eNOS.
Side Effects
- Gastrointestinal discomfort
- Hypotension at high doses
- Headache
- See individual component profiles for full side effects
Drug & Supplement Interactions
- See L-arginine and L-citrulline entries for comprehensive interaction profiles
- PDE5 inhibitors (excessive vasodilation risk)
- Nitrates (excessive vasodilation risk)
- Antihypertensives (additive blood pressure lowering)
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Related Ingredients
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