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HeartCited

Chitosan
Chitosan

fiber

别名: Deacetylated Chitin, Poly-D-Glucosamine, Chitosan HCl

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About





            

                
Chitosan is a positively charged polysaccharide derived from crustacean shells that binds bile acids and dietary fat in the intestine. A 2018 Cochrane review of 14 RCTs found a statistically significant but clinically modest reduction in total cholesterol, though its practical clinical significance is debated.

            

        

        

        
        
        

            

  
How It Works





            

                
A positively charged polysaccharide that electrostatically binds negatively charged bile acids and dietary fat forming insoluble complexes excreted in feces; reduces dietary fat absorption by 1-5%; bile acid sequestration triggers hepatic LDL receptor upregulation similar to bile acid sequestrant drugs.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Cholesterol (Hyperlipidemia)
                                    
                                
                                
                                    C

                                
                                
                                    14
                                
                                
                                    1100
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        High Triglycerides (Hypertriglyceridemia)
                                    
                                
                                
                                    D

                                
                                
                                    3
                                
                                
                                    200
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Constipation
                
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                    Gas and bloating
                
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                    Nausea
                
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                    Allergic reactions in those with shellfish allergy (contraindicated)
                
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Drug & Supplement Interactions





            
    
                
                
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                    Fat-soluble vitamins (A, D, E, K — may reduce absorption)
                
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                    Oral medications (may bind and reduce absorption — separate by 2 hours)
                
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                    Warfarin (may reduce vitamin K absorption, affecting INR)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Psyllium
                    
                
                
                
                    Plant Sterols/Stanols
                    
                
                
                
                    Beta-Glucan
                    
                
                
            

        

        
    


    
    












    

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