PsylliumPsyllium
fiber
别名: Psyllium Husk, Ispaghula, Metamucil, Plantago ovata
About
Psyllium is a soluble gel-forming fiber with an FDA-approved health claim for cholesterol reduction. A 2018 meta-analysis of 28 RCTs found psyllium at 10g/day reduced LDL cholesterol by 12.5 mg/dL. The AHA/ACC endorse psyllium as part of therapeutic lifestyle changes for hypercholesterolemia.
How It Works
Soluble gel-forming fiber that binds bile acids in the intestinal lumen, forcing the liver to use circulating cholesterol to synthesize new bile acids, thereby reducing LDL cholesterol; forms a viscous gel slowing glucose absorption and reducing postprandial insulin spikes; promotes beneficial gut bacteria fermentation producing short-chain fatty acids.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| High Cholesterol (Hyperlipidemia) | A | 28 | 2000 | 查看 → |
Side Effects
- Bloating and gas (especially when starting — resolves with gradual titration)
- Abdominal cramping
- Choking hazard if taken without adequate water
- Allergic reactions (rare, in healthcare workers with occupational exposure)
Drug & Supplement Interactions
- All oral medications (may reduce absorption — take medications 1-2 hours before psyllium)
- Diabetes medications (additive blood sugar lowering effect)
- Lithium (may reduce absorption)
- Carbamazepine (may reduce absorption)
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Related Ingredients
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