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HeartCited

Beta-Glucan
Beta-Glucan

fiber

别名: Oat Beta-Glucan, Barley Beta-Glucan, Beta-1,3/1,4-Glucan, OatWell

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About





            

                
Oat beta-glucan is a soluble fiber with both FDA and EFSA-approved health claims for cardiovascular risk reduction. A 2014 meta-analysis of 28 RCTs found 3g/day oat beta-glucan reduced LDL cholesterol by 9.7 mg/dL. The dose-dependent cholesterol lowering effect (5-7% LDL reduction) is modest but additive to other interventions.

            

        

        

        
        
        

            

  
How It Works





            

                
Soluble beta-1,3/1,4-glucan fiber forms a viscous gel trapping bile acids and cholesterol, reducing intestinal absorption; increases bile acid excretion forcing hepatic conversion of cholesterol; fermented by colonic bacteria producing propionate, which may inhibit hepatic cholesterol synthesis; also modulates innate immunity via Dectin-1 receptor activation.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Cholesterol (Hyperlipidemia)
                                    
                                
                                
                                    A

                                
                                
                                    28
                                
                                
                                    2500
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Bloating and gas (especially when starting)
                
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                    Mild abdominal discomfort
                
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                    Generally very well-tolerated
                
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Drug & Supplement Interactions





            
    
                
                
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                    May slow absorption of oral medications (take medications 1 hour apart)
                
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                    Diabetes medications (additive blood sugar lowering)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Psyllium
                    
                
                
                
                    Plant Sterols/Stanols
                    
                
                
                
                    Chitosan
                    
                
                
            

        

        
    


    
    












    

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