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HeartCited

Calcium
Calcium

mineral

别名: Calcium Carbonate, Calcium Citrate, Calcium Hydroxyapatite

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About





            

                
Calcium is essential for cardiac muscle contraction-relaxation cycling and maintaining normal heart rhythm. However, a 2010 BMJ meta-analysis of 11 RCTs found calcium supplements (without vitamin D) were associated with a 31% increased risk of myocardial infarction. Current AHA guidance suggests obtaining calcium preferentially from food sources rather than supplements.

            

        

        

        
        
        

            

  
How It Works





            

                
Essential for cardiac muscle contraction-relaxation cycling through calcium-induced calcium release from the sarcoplasmic reticulum; maintains normal heart rhythm; low dietary calcium associated with increased PTH and RAAS activation which may promote hypertension; calcium from food sources may have different cardiovascular effects than supplemental calcium.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Blood Pressure (Hypertension)
                                    
                                
                                
                                    C

                                
                                
                                    13
                                
                                
                                    1500
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Constipation (especially carbonate form)
                
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                    Potential increased MI risk with high-dose supplements (controversial)
                
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                    Kidney stones at excessive doses
                
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                    Gas, bloating
                
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Drug & Supplement Interactions





            
    
                
                
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                    Thyroid medications (separate by 4 hours)
                
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                    Bisphosphonates (separate by 30-60 minutes)
                
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                    Iron supplements (reduced absorption — separate by 2 hours)
                
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                    Certain antibiotics (reduced absorption)
                
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                    Vitamin K2 (may help direct supplemental calcium to bones, not arteries)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Magnesium
                    
                
                
                
                    Potassium
                    
                
                
                
                    Selenium
                    
                
                
            

        

        
    


    
    












    

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