CalciumCalcium
mineral
다른 이름: Calcium Carbonate, Calcium Citrate, Calcium Hydroxyapatite
About
Calcium is essential for cardiac muscle contraction-relaxation cycling and maintaining normal heart rhythm. However, a 2010 BMJ meta-analysis of 11 RCTs found calcium supplements (without vitamin D) were associated with a 31% increased risk of myocardial infarction. Current AHA guidance suggests obtaining calcium preferentially from food sources rather than supplements.
How It Works
Essential for cardiac muscle contraction-relaxation cycling through calcium-induced calcium release from the sarcoplasmic reticulum; maintains normal heart rhythm; low dietary calcium associated with increased PTH and RAAS activation which may promote hypertension; calcium from food sources may have different cardiovascular effects than supplemental calcium.
Evidence For Conditions
| 건강 상태 | 등급 | 연구 | 참여자 | |
|---|---|---|---|---|
| High Blood Pressure (Hypertension) | C | 13 | 1500 | 보기 → |
Side Effects
- Constipation (especially carbonate form)
- Potential increased MI risk with high-dose supplements (controversial)
- Kidney stones at excessive doses
- Gas, bloating
Drug & Supplement Interactions
- Thyroid medications (separate by 4 hours)
- Bisphosphonates (separate by 30-60 minutes)
- Iron supplements (reduced absorption — separate by 2 hours)
- Certain antibiotics (reduced absorption)
- Vitamin K2 (may help direct supplemental calcium to bones, not arteries)
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Related Ingredients
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