循证 补充剂评测
Every heart claim cited.
We read the cardiovascular studies so you don't have to.
Evidence-based supplement research you can trust. We analyze peer-reviewed clinical studies from PubMed and grade every supplement ingredient on a transparent A–D scale. No sponsored rankings, no manufacturer influence — just science.
Featured Ingredients
Coenzyme Q10 (CoQ10)
coenzymeEssential cofactor in mitochondrial electron transport chain (Complex I-III) supporting cellular energy production (ATP) in high-demand cardiac tissue; potent lipid-soluble …
Vitamin D
vitaminBinds to vitamin D receptors (VDR) on cardiomyocytes, vascular smooth muscle, and endothelial cells regulating calcium handling and contractile function; …
Vitamin K2
vitaminActivates matrix Gla protein (MGP) — the most potent natural inhibitor of arterial calcification — through gamma-carboxylation; directs calcium deposition …
Niacin (Vitamin B3)
vitaminActivates GPR109A (HCA2) receptor in adipocytes reducing lipolysis and free fatty acid flux to the liver, decreasing hepatic VLDL/triglyceride production; …
Magnesium
mineralEssential cofactor for >300 enzymatic reactions regulating vascular tone; acts as a natural calcium channel blocker relaxing vascular smooth muscle; …
Omega-3 Fatty Acids (EPA/DHA)
fatty_acidLong-chain polyunsaturated fatty acids that incorporate into cell membranes modulating inflammatory signaling via reduced arachidonic acid conversion to pro-inflammatory eicosanoids; …
Top Conditions
High Cholesterol (Hyperlipidemia)
38% of US adults have total cholesterol >=200 mg/dL; 12% have LDL >=160 mg/dL
Atherosclerosis
Subclinical atherosclerosis present in >50% of adults over 40
Heart Failure
6.7 million US adults; prevalence increases with age (10% in adults >65)
Cardiac Arrhythmia
Atrial fibrillation: 33.5 million worldwide; PVCs: present in 75% of healthy adults
Peripheral Artery Disease (PAD)
8.5 million US adults; 12-20% of adults >60 years
High Blood Pressure (Hypertension)
47% of US adults (116 million); ~1.28 billion adults worldwide
Recent Evidence Updates
Guides & Resources
Exercise for Heart Health: How Supplements Can Support Your Routine
Regular physical activity is unequivocally one of the most powerful interventions for cardiovascular health, with effects that rival or exceed many pharmaceutical treatments. The American …
lifestyleThe Mediterranean Diet and Heart Supplements: A Complete Guide
The Mediterranean diet stands as the most well-validated dietary pattern for cardiovascular disease prevention, supported by decades of epidemiological evidence and confirmed by the landmark …
safetyTaking Supplements While on Blood Thinners: Essential Cautions
Anticoagulant and antiplatelet medications — including warfarin, heparin, direct oral anticoagulants (DOACs such as apixaban, rivaroxaban, edoxaban, and dabigatran), aspirin, clopidogrel, and prasugrel — are …
Evidence Grading System
Every supplement claim on this site is graded on an A–D scale based on peer-reviewed clinical research from PubMed. Our algorithm evaluates study design (RCTs rank highest), consistency of results, sample sizes, and the overall body of evidence. No manufacturer sponsorship influences our grades.
Multiple randomized controlled trials (RCTs) or meta-analyses with consistent positive results and large sample sizes.
At least one RCT with mostly consistent results across studies. Evidence suggests benefit but more research may be needed.
Small studies or observational data with some positive signals. Promising but insufficient for strong recommendations.
In vitro studies, case reports, or pilot studies only. Early-stage research that requires clinical validation.
How It Works
无广告。无赞助排名。只有科学。
研究中心
我们在 PubMed 上检索每一项关于补充剂成分的临床研究。
提取
我们提取关键发现——样本量、研究类型和结果。
A 至 F 级
我们像成绩单一样对证据进行分级——从 A(有力)到 F(阴性)。
明确答案
几秒内获得明确答案——这种补充剂是否真的有效?
Cited Health Network
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FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。