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HeartCited

Resveratrol ： Atherosclerosis

C

Improves FMD and reduces inflammatory markers. RESVACE trial was negative for cardiac function in heart failure. Bioavailability challenges limit clinical translation.

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            C

        

        

            
結論

            
            
Improves FMD and reduces inflammatory markers. RESVACE trial was negative for cardiac function in heart failure. Bioavailability challenges limit clinical translation.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
5

        
研究数

    

    

        
400

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
150-500 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
250-500 mg/day trans-resveratrol

                    

                    
                

                
                

                    上限量： Not formally established; GI discomfort common above 1,000 mg/day
                

                
            

            

            

            
            

                推奨摂取タイミング： With meals; bioavailability enhanced by piperine co-supplementation
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                        
  • 
                            ⚠
                            May have estrogenic activity at high doses
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may inhibit platelet aggregation)
                        
    • 
                        
                        
  • 
                            ●
                            CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
                        
    • 
                        
                        
  • 
                            ●
                            Blood pressure medications (additive hypotensive effect)
                        
    • 
                        
                        
  • 
                            ●
                            Estrogen-sensitive conditions (weak estrogenic activity)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Not formally established; GI discomfort common above 1,000 mg/day
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Resveratrol help with Atherosclerosis?
            
        
        

            Based on 5 studies with 400 participants, there is limited but promising evidence that Resveratrol may support Atherosclerosis management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Resveratrol should I take for Atherosclerosis?
            
        
        

            Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Resveratrol?
            
        
        

            Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Resveratrol and Atherosclerosis?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Resveratrol 他の症状・状態について

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            B

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。