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Quercetin ： Atherosclerosis

D 研究 予備的な研究（実験室研究、症例報告）のみが存在します。

In vitro evidence for PCSK9 inhibition and reduced foam cell formation. Limited human data on atherosclerosis endpoints specifically.

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            D

        

        

            
結論

            
            
In vitro evidence for PCSK9 inhibition and reduced foam cell formation. Limited human data on atherosclerosis endpoints specifically.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Other
                
                
                
                
            

            
                Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating …
            
            

                
                Dose: None
                
                
                vs: Allergic rhinitis mouse model vs control
                
                
                Outcome: Rhinitis symptoms and serum inflammatory indicators
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: Allergic rhinitis mouse model

            
        

        
        

            

                
                    Other
                
                
                
                
            

            
                Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes …
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Inflammatory markers
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Using herbal medicine to target the "microbiota-metabolism-immunity" axis as possible therapy for cardiovascular disease.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Gut microbiota composition
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: None

            
        

        
        

            

                
                    In Vitro
                
                
                
                
            

            
                Dietary Polyphenols in the Prevention of Stroke.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Stroke prevention
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: General population (CVD risk)

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
研究数

    

    

        
100

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating Allergic Rhinitis Mouse Model based …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Current computer-aided drug …
                        2025
                        
                        2 件の引用
                        
                    

                

                
                

                    

                        
                            Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Iranian journal of …
                        2024
                        
                        4 件の引用
                        
                    

                

                
                

                    

                        
                            Using herbal medicine to target the "microbiota-metabolism-immunity" axis as possible therapy for cardiovascular disease.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Pharmacological research
                        2019
                        
                        31 件の引用
                        
                    

                

                
                

                    

                        
                            Dietary Polyphenols in the Prevention of Stroke.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Oxidative medicine and …
                        2017
                        
                        87 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
500-1,000 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
500-730 mg/day

                    

                    
                

                
                

                    上限量： Not formally established; up to 1,000 mg/day used in clinical trials
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： With meals; vitamin C co-supplementation may enhance bioavailability
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Tingling in extremities (rare, high doses)
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Antibiotics (quinolones — may reduce efficacy)
                        
    • 
                        
                        
  • 
                            ●
                            Cyclosporine (may increase blood levels)
                        
    • 
                        
                        
  • 
                            ●
                            Anticoagulants (may have mild antiplatelet effect)
                        
    • 
                        
                        
  • 
                            ●
                            Blood pressure medications (additive effect)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Not formally established; up to 1,000 mg/day used in clinical trials
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Quercetin help with Atherosclerosis?
            
        
        

            Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Quercetin may support Atherosclerosis management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Quercetin should I take for Atherosclerosis?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Quercetin?
            
        
        

            Reported side effects may include Generally well-tolerated, Headache (rare), Mild gastrointestinal discomfort, Tingling in extremities (rare, high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Quercetin and Atherosclerosis?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Quercetin 他の症状・状態について

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Sihong Huang et al..
      Curr Comput Aided Drug Des.
      2025.
      Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating Allergic Rhinitis Mouse Model based …
      doi:10.2174/0115734099299714240516160158
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Masoumeh Shamsi et al..
      Iran J Pharm Res.
      2024.
      Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin …
      doi:10.5812/ijpr-151428
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Wang Anlu et al..
      Pharmacol Res.
      2019.
      Using herbal medicine to target the "microbiota-metabolism-immunity" axis as possible therapy for cardiovascular disease.
      doi:10.1016/j.phrs.2019.02.018
      PubMed
    
    4. 
    
    
  4. 
      [4]
      A Tressera-Rimbau et al..
      Oxid Med Cell Longev.
      2017.
      Dietary Polyphenols in the Prevention of Stroke.
      doi:10.1155/2017/7467962
      PubMed
    
    5. 
    
  















    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。