Resveratrol per High Blood Pressure (Hypertension)

Q: Does Resveratrol help with High Blood Pressure (Hypertension)?

Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

Q: How much Resveratrol should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Resveratrol?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

B Evidenze Almeno un trial randomizzato lo supporta, con risultati per lo più coerenti.

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'heartcited.com'; const params = 'ingredient\u003Dresveratrol\u0026condition\u003Dhigh\u002Dblood\u002Dpressure'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

In sintesi

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Key Study Findings

Review

Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk.

Dose: None vs: None Outcome: None Effetto: None None

Popolazione: review of nutrition and lifestyle interventions for dyslipidemia and cardiometabolic risk

Review

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.

Dose: None vs: None Outcome: None Effetto: None None

Popolazione: review of age-related cardiac dysfunction and heart failure mechanisms

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Effetto: ~50% risk reduction None

Popolazione: Pregnant women with low calcium intake

Systematic Review

The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.

Dose: None vs: Placebo or no treatment Outcome: Cardiometabolic changes in menopausal women Effetto: None None

Popolazione: Menopausal women

Controlled Clinical Trial

Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway.

Dose: None vs: Model group (no RES) and sham control Outcome: Cerebral aneurysm formation Effetto: None P<0.05

Popolazione: Mice with induced hypertension CA model

Review

The Role of Resveratrol Administration in Human Obesity.

Dose: None vs: None Outcome: None Effetto: None None

Popolazione: Obese adults

Key Statistics

Studi

600

Partecipanti

↑

Positive

Grado

Referenced Papers

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. Review

ESC heart failure 2025 58 citazioni

Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. Review

Nutrients 2025 32 citazioni

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 citazioni

The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. Other

Cardiovascular & hematological … 2025

Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. Other

Acta biochimica Polonica 2022 10 citazioni

The Role of Resveratrol Administration in Human Obesity. Review

International journal of … 2021 50 citazioni

Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. Other

Nutrients 2020 49 citazioni

Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. Other

Nutrients 2020 16 citazioni

Nutritional prevention of cognitive decline and dementia. Review

Acta bio-medica : … 2018 103 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

general:: 150-500 mg/day
cardiovascularsupport:: 250-500 mg/day trans-resveratrol

Limite massimo: Not formally established; GI discomfort common above 1,000 mg/day

Dosaggi studiati nella ricerca

Dosaggio	Durata	Effetto	N
None	--	Positive	--
None	--	Neutral	--
500 mg daily	--	Positive	--
None	--	Positive	--
None	--	Positive	--
None	--	Mixed	--
75 mg	14 weeks	Positive	129
None	--	Mixed	--

Momento migliore per l'assunzione: With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

Effetti collaterali segnalati

⚠ Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
⚠ Headache
⚠ May have estrogenic activity at high doses

Interazioni note

● Anticoagulants (may inhibit platelet aggregation)
● CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
● Blood pressure medications (additive hypotensive effect)
● Estrogen-sensitive conditions (weak estrogenic activity)

Livello di assunzione massimo tollerabile: Not formally established; GI discomfort common above 1,000 mg/day

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Resveratrol help with High Blood Pressure (Hypertension)?

Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

How much Resveratrol should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Resveratrol?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Altri ingredienti per High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Magnesium B Potassium B Quercetin B Grape Seed Extract B

Resveratrol per altre condizioni

Atherosclerosis C

Verdetto rapido

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Evidence Strength72%

High confidence

Analisi degli studi

RCT (0)Meta (0)Other (10)

Confronta le alternative

Scoprite come si confrontano altri ingredienti per questa condizione.

Visualizza tutti gli ingredienti per High Blood Pressure (Hypertension)

Approfondimenti

References

[1] Zhuyubing Fang et al.. ESC Heart Fail. 2025. Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. doi:10.1002/ehf2.14947 PubMed
[2] Hygerta Berisha et al.. Nutrients. 2025. Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. doi:10.3390/nu17050776 PubMed
[3] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[4] Ali Amini et al.. Cardiovasc Hematol Disord Drug Targets. 2025. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. doi:10.2174/011871529X398468250910225946 PubMed
[5] Tao Jin et al.. Acta Biochim Pol. 2022. Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. doi:10.18388/abp.2020_5982 PubMed
[6] Laura M Mongioì et al.. Int J Mol Sci. 2021. The Role of Resveratrol Administration in Human Obesity. doi:10.3390/ijms22094362 PubMed
[7] Jay Jay Thaung Zaw et al.. Nutrients. 2020. Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. doi:10.3390/nu12030828 PubMed
[8] Raúl Francisco Pastor et al.. Nutrients. 2020. Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. doi:10.3390/nu12103149 PubMed
[9] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.

Resveratrol per High Blood Pressure (Hypertension)

Embed This Widget

In sintesi

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Dosaggi di uso comune

Dosaggi studiati nella ricerca

Safety & Side Effects

Effetti collaterali segnalati

Interazioni note

Frequently Asked Questions

Related Evidence

Altri ingredienti per High Blood Pressure (Hypertension)

Resveratrol per altre condizioni

References