Skip to main content
HeartCited

L-Citrulline
L-Citrulline

amino_acid

Juga dikenal sebagai: Citrulline, Citrulline Malate, L-Citrulline DL-Malate

<\/script>\n
`; }, get iframeSnippet() { const domain = 'heartcited.com'; const params = 'ingredient\u003Dl\u002Dcitrulline'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  




    






    
    

        
        
        

            

  
About





            

                
L-Citrulline is converted to L-arginine in the kidneys, bypassing hepatic first-pass metabolism and maintaining sustained plasma arginine levels more effectively than direct arginine supplementation. A 2019 meta-analysis of 7 RCTs found L-citrulline at 3-6g/day significantly reduced systolic blood pressure by 4.1 mmHg.

            

        

        

        
        
        

            

  
How It Works





            

                
Converted to L-arginine in the kidneys bypassing hepatic first-pass metabolism, maintaining sustained plasma arginine levels; this recycling pathway maintains nitric oxide production more effectively than direct arginine supplementation; citrulline also buffers ammonia during high-demand cardiac states.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                Kondisi
                                Peringkat
                                Studi
                                Peserta
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Blood Pressure (Hypertension)
                                    
                                
                                
                                    C

                                
                                
                                    7
                                
                                
                                    400
                                
                                
                                    
                                        Lihat →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
  • 
                    
                    Generally well-tolerated
                
    • 
                
                
  • 
                    
                    Mild gastrointestinal discomfort at high doses
                
    • 
                
                
  • 
                    
                    Heartburn (rare)
                
    • 
                
            

        

        

        
        
        

            

  
Drug & Supplement Interactions





            
    
                
                
  • 
                    
                    Antihypertensives (additive blood pressure lowering)
                
    • 
                
                
  • 
                    
                    PDE5 inhibitors (excessive vasodilation risk)
                
    • 
                
                
  • 
                    
                    Nitrates (excessive vasodilation risk)
                
    • 
                
            

            

                Selalu informasikan kepada tenaga kesehatan Anda tentang semua suplemen yang Anda konsumsi.Selalu informasikan penyedia layanan kesehatan Anda tentang semua suplemen yang Anda konsumsi.
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    L-Arginine
                    
                
                
                
                    Taurine
                    
                
                
                
                    Nattokinase
                    
                
                
            

        

        
    


    
    












    

        Penafian FDA:
        Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.