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Olive Leaf Extract لـ Atherosclerosis

D الأبحاث توجد أبحاث أولية فحسب (دراسات مختبرية، تقارير حالات).

Oleuropein may help reduce ox-LDL (a key atherogenic particle). PREDIMED trial supports cardiovascular benefit of olive polyphenols, but used oil rather than leaf extract specifically.

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الخلاصة

            
            
Oleuropein may help reduce ox-LDL (a key atherogenic particle). PREDIMED trial supports cardiovascular benefit of olive polyphenols, but used oil rather than leaf extract specifically.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                
                8 weeks
                
                
                Double-blind
                
            

            
                Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers …
            
            

                
                Dose: 180 mg/d
                
                
                مقابل: None
                
                
                Outcome: lipid levels
                
                
                التأثير: None
                
                
                p < 0.001
                
            

            
            
المجتمع المدروس: Patients with dyslipidemia

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
الدراسات

    

    

        
100

        
المشاركون

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
التقييم

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with …
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2023
                        
                        8 اقتباسات
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
الجرعات الشائعة

                

                    
                    

                        
general:

                        
500 mg BID

                    

                    
                    

                        
oleuropeincontent:

                        
15-20% standardization

                    

                    
                    

                        
standardizedextract:

                        
500-1,000 mg/day (EFLA 943)

                    

                    
                

                
                

                    الحد الأعلى: Not formally established; well-tolerated up to 1,000 mg/day in clinical trials
                

                
            

            

            
            

                
الجرعات المدروسة في الأبحاث

                

                    

                        
                            

                                الجرعة
                                المدة
                                التأثير
                                ن
                            

                        
                        
                            
                            

                                180 mg/d
                                8 weeks
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                أفضل وقت للتناول: With meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
الآثار الجانبية المُبلّغ عنها

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness (if blood pressure drops significantly)
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache (rare)
                        
    • 
                        
                    

                

                

                
                

                    
التفاعلات المعروفة

                    
    
                        
                        
  • 
                            ●
                            Antihypertensives (additive blood pressure lowering — monitor BP)
                        
    • 
                        
                        
  • 
                            ●
                            Diabetes medications (may lower blood sugar)
                        
    • 
                        
                        
  • 
                            ●
                            Anticoagulants (mild theoretical interaction)
                        
    • 
                        
                    

                

                

                
                

                    

                        الحد الأقصى المسموح به: Not formally established; well-tolerated up to 1,000 mg/day in clinical trials
                    

                

                
            

            

                استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Olive Leaf Extract help with Atherosclerosis?
            
        
        

            Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Olive Leaf Extract may support Atherosclerosis management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Olive Leaf Extract should I take for Atherosclerosis?
            
        
        

            Studies have used various dosages. A commonly studied range is 500 mg BID. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Olive Leaf Extract?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild gastrointestinal discomfort, Dizziness (if blood pressure drops significantly), Headache (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Olive Leaf Extract and Atherosclerosis?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Olive Leaf Extract لحالات أخرى

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Nicholas Angelopoulos et al..
      Nutrients.
      2023.
      Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with …
      doi:10.3390/nu15122682
      PubMed
    
    2. 
    
  















    

        إخلاء مسؤولية FDA:
        لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.