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HeartCited

Hawthorn 用于 Heart Failure

B

Cochrane review of 14 RCTs: improved exercise tolerance and symptom scores. SPICE trial (2,681 patients) showed trend toward benefit. German Commission E-approved for declining cardiac function (NYHA I-II).

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            B

        

        

            
结论

            
            
Cochrane review of 14 RCTs: improved exercise tolerance and symptom scores. SPICE trial (2,681 patients) showed trend toward benefit. German Commission E-approved for declining cardiac function (NYHA I-II).

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
14

        
研究数量

    

    

        
3800

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
等级

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
450-900 mg/day standardized extract (WS 1442 or LI 132)

                    

                    
                    

                        
standardization:

                        
18.75% OPCs or 2.2% flavonoids

                    

                    
                

                
                

                    上限： Not formally established; up to 1,800 mg/day used in the SPICE trial
                

                
            

            

            

            
            

                最佳服用时间： With meals; effects require 6-8 weeks of continuous use
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea
                        
    • 
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Cardiac glycosides (digoxin — may enhance inotropic effects)
                        
    • 
                        
                        
  • 
                            ●
                            Antihypertensives (additive blood pressure lowering)
                        
    • 
                        
                        
  • 
                            ●
                            Beta-blockers (additive cardiac effects)
                        
    • 
                        
                        
  • 
                            ●
                            PDE5 inhibitors (additive vasodilation)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not formally established; up to 1,800 mg/day used in the SPICE trial
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Hawthorn help with Heart Failure?
            
        
        

            Based on 14 studies with 3,800 participants, there is moderate evidence from clinical studies that Hawthorn may support Heart Failure management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Hawthorn should I take for Heart Failure?
            
        
        

            Studies have used various dosages. A commonly studied range is 450-900 mg/day standardized extract (WS 1442 or LI 132). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Hawthorn?
            
        
        

            Reported side effects may include Generally well-tolerated, Dizziness, Nausea, Gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Hawthorn and Heart Failure?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 14 peer-reviewed studies with 3,800 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Hawthorn 用于其他健康状况

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

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