What is the recommended dosage for Quercetin?

General: 500-1,000 mg/day; Blood Pressure Support: 500-730 mg/day

What are the side effects of Quercetin?

Potential side effects include: Generally well-tolerated, Headache (rare), Mild gastrointestinal discomfort, Tingling in extremities (rare, high doses).

What is quercetin and how may it support cardiovascular health?

Quercetin is a flavonoid found in onions, apples, and berries with antioxidant and anti-inflammatory properties. Meta-analyses of RCTs suggest quercetin may reduce blood pressure, particularly in hypertensive individuals. It may also improve endothelial function and reduce LDL oxidation.

What dosage of quercetin has been studied for cardiovascular benefits?

Clinical trials have used 100–1,000 mg of quercetin per day. Blood pressure reductions were most consistent at doses of 500 mg or higher daily for at least 8 weeks. Quercetin dihydrate and quercetin-3-glucoside are commonly studied forms. Bioavailability may be improved with co-administration of vitamin C.

What are the potential side effects of quercetin?

Quercetin is generally well tolerated at doses up to 1,000 mg daily. Side effects are rare but may include headache and tingling in extremities. Quercetin may interact with antibiotics (fluoroquinolones), cyclosporine, and drugs metabolized by CYP3A4. Very high doses may have pro-oxidant effects.

Quercetin
Quercetin

antioxidant

다른 이름: Quercetin Dihydrate, Quercetin Phytosome, Isoquercetin

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About

Quercetin is a ubiquitous dietary flavonoid that reduces blood pressure through endothelium-dependent nitric oxide release and ACE inhibition. A 2020 meta-analysis of 17 RCTs found quercetin at >=500 mg/day reduced systolic blood pressure by 3.09 mmHg and diastolic by 2.86 mmHg, with greater effects in hypertensive subjects.

How It Works

Inhibits LDL oxidation and foam cell formation; reduces blood pressure through direct vasorelaxation via endothelium-dependent nitric oxide release; inhibits ACE activity; anti-inflammatory via NF-kB, COX-2, and lipoxygenase inhibition; reduces platelet aggregation; may inhibit PCSK9 expression reducing LDL receptor degradation.

Evidence For Conditions

건강 상태	등급	연구	참여자
High Blood Pressure (Hypertension)	B	17	900	보기 →
Atherosclerosis	D	2	100	보기 →

Side Effects

Generally well-tolerated
Headache (rare)
Mild gastrointestinal discomfort
Tingling in extremities (rare, high doses)

Drug & Supplement Interactions

Antibiotics (quinolones — may reduce efficacy)
Cyclosporine (may increase blood levels)
Anticoagulants (may have mild antiplatelet effect)
Blood pressure medications (additive effect)

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Related Ingredients

Resveratrol Grape Seed Extract Astaxanthin Lycopene

핵심 정보

용량: General: 500-1,000 mg/day; Blood_Pressure_Support: 500-730 mg/day
제형: capsule tablet powder
천연 원료: Onions (especially red), Apples, Berries, Broccoli, Capers, Green tea, Red wine
상한 섭취량: Not formally established; up to 1,000 mg/day used in clinical trials
권장 복용 시간: With meals; vitamin C co-supplementation may enhance bioavailability

근거 요약

High Blood Pressure (Hypertension) B

Atherosclerosis D

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.