What is the recommended dosage for Quercetin?

General: 500-1,000 mg/day; Blood Pressure Support: 500-730 mg/day

What are the side effects of Quercetin?

Potential side effects include: Generally well-tolerated, Headache (rare), Mild gastrointestinal discomfort, Tingling in extremities (rare, high doses).

What is quercetin and how may it support cardiovascular health?

Quercetin is a flavonoid found in onions, apples, and berries with antioxidant and anti-inflammatory properties. Meta-analyses of RCTs suggest quercetin may reduce blood pressure, particularly in hypertensive individuals. It may also improve endothelial function and reduce LDL oxidation.

What dosage of quercetin has been studied for cardiovascular benefits?

Clinical trials have used 100–1,000 mg of quercetin per day. Blood pressure reductions were most consistent at doses of 500 mg or higher daily for at least 8 weeks. Quercetin dihydrate and quercetin-3-glucoside are commonly studied forms. Bioavailability may be improved with co-administration of vitamin C.

What are the potential side effects of quercetin?

Quercetin is generally well tolerated at doses up to 1,000 mg daily. Side effects are rare but may include headache and tingling in extremities. Quercetin may interact with antibiotics (fluoroquinolones), cyclosporine, and drugs metabolized by CYP3A4. Very high doses may have pro-oxidant effects.

Quercetin
Quercetin

antioxidant

يُعرف أيضاً بـ: Quercetin Dihydrate, Quercetin Phytosome, Isoquercetin

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About

Quercetin is a ubiquitous dietary flavonoid that reduces blood pressure through endothelium-dependent nitric oxide release and ACE inhibition. A 2020 meta-analysis of 17 RCTs found quercetin at >=500 mg/day reduced systolic blood pressure by 3.09 mmHg and diastolic by 2.86 mmHg, with greater effects in hypertensive subjects.

How It Works

Inhibits LDL oxidation and foam cell formation; reduces blood pressure through direct vasorelaxation via endothelium-dependent nitric oxide release; inhibits ACE activity; anti-inflammatory via NF-kB, COX-2, and lipoxygenase inhibition; reduces platelet aggregation; may inhibit PCSK9 expression reducing LDL receptor degradation.

Evidence For Conditions

الحالة	التقييم	الدراسات	المشاركون
High Blood Pressure (Hypertension)	B	17	900	عرض →
Atherosclerosis	D	2	100	عرض →

Side Effects

Generally well-tolerated
Headache (rare)
Mild gastrointestinal discomfort
Tingling in extremities (rare, high doses)

Drug & Supplement Interactions

Antibiotics (quinolones — may reduce efficacy)
Cyclosporine (may increase blood levels)
Anticoagulants (may have mild antiplatelet effect)
Blood pressure medications (additive effect)

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Related Ingredients

Resveratrol Grape Seed Extract Astaxanthin Lycopene

حقائق سريعة

الجرعة: General: 500-1,000 mg/day; Blood_Pressure_Support: 500-730 mg/day
الأشكال الدوائية: capsule tablet powder
المصادر الطبيعية: Onions (especially red), Apples, Berries, Broccoli, Capers, Green tea, Red wine
الحد الأعلى: Not formally established; up to 1,000 mg/day used in clinical trials
أفضل وقت: With meals; vitamin C co-supplementation may enhance bioavailability

ملخص الأدلة

High Blood Pressure (Hypertension) B

Atherosclerosis D

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