Lycopene per Atherosclerosis

D Ricerca Esiste solo ricerca preliminare (studi di laboratorio, segnalazioni di casi).

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

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In sintesi

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

Key Study Findings

Other

Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine …

Dose: 50 mg/kg lycopene in mice vs: HFD control mice Outcome: Cognitive function (Y-maze, MWM, novel object recognition) Effetto: None None

Popolazione: HFD-induced obese male C57BL/6 mice

Review

Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications.

Dose: None vs: None Outcome: None Effetto: None None

Popolazione: review of plant-derived anti-inflammatory compounds for chronic disease prevention

Observational Study n=60

Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive …

Dose: None vs: None Outcome: Carotenoid moderation of cfPWV-cognition relationship Effetto: Beta=0.53, p=0.04 for lutein moderation 0.02

Popolazione: Adults, mean age 38.6, 70% female

Meta-Analysis

Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.

Dose: None vs: Placebo Outcome: Blood pressure Effetto: None None

Popolazione: None

systematic review n=90

A systematic review on the impact of nutrition and possible supplementation on the deficiency of …

Dose: None vs: Placebo Effetto: None None

Randomized Controlled Trial

Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.

Dose: None vs: None Outcome: Cognitive decline Effetto: None None

Popolazione: Alzheimer's disease patients

Key Statistics

Studi

200

Partecipanti

↑

Positive

Grado

Referenced Papers

Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. Review

International journal of … 2025 32 citazioni

Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. Other

Clinical nutrition (Edinburgh, … 2025 1 citazioni

Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. Other

The Journal of … 2025

A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … Systematic Review

Archives of gynecology … 2024 18 citazioni

Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. Review

International journal of … 2024 11 citazioni

Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. Meta-Analysis

Nutrients 2024 6 citazioni

Sleep symptoms associated with intake of specific dietary nutrients. Other

Journal of sleep … 2014 236 citazioni

Carotenoids and cardiovascular disease. Review

Current atherosclerosis reports 2009 122 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

general:: 6-15 mg/day
cardiovascularsupport:: 15-30 mg/day

Limite massimo: Not formally established; up to 75 mg/day used in clinical trials

Dosaggi studiati nella ricerca

Dosaggio	Durata	Effetto	N
50 mg/kg lycopene in mice	--	Positive	--
None	--	Positive	--
None	--	Positive	60
None	--	Neutral	--
None	--	Negative	90
None	--	Positive	--
None	--	Mixed	--

Momento migliore per l'assunzione: With meals containing fat (cooking with olive oil enhances absorption 2-3x)

Safety & Side Effects

Effetti collaterali segnalati

⚠ Generally well-tolerated
⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible

Interazioni note

● Blood pressure medications (may have mild additive effect)
● Beta-carotene (may compete for absorption)

Livello di assunzione massimo tollerabile: Not formally established; up to 75 mg/day used in clinical trials

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Lycopene help with Atherosclerosis?

Based on 3 studies with 200 participants, there is preliminary evidence that needs more research that Lycopene may support Atherosclerosis management. Our evidence grade is D (Very Early Research).

How much Lycopene should I take for Atherosclerosis?

Studies have used various dosages. A commonly studied range is 6-15 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lycopene?

Reported side effects may include Generally well-tolerated, Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lycopene and Atherosclerosis?

We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.

Altri ingredienti per Atherosclerosis

Nattokinase B Vitamin E C Resveratrol C Quercetin D Flaxseed Oil D Olive Leaf Extract D

Lycopene per altre condizioni

High Blood Pressure (Hypertension) B

Verdetto rapido

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

Evidence Strength30%

Low confidence

Analisi degli studi

RCT (0)Meta (1)Other (2)

Confronta le alternative

Scoprite come si confrontano altri ingredienti per questa condizione.

Visualizza tutti gli ingredienti per Atherosclerosis

Approfondimenti

References

[1] Kazuhiko Nakadate et al.. Int J Mol Sci. 2025. Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. doi:10.3390/ijms26115206 PubMed
[2] Yuqing Wu et al.. Clin Nutr. 2025. Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. doi:10.1016/j.clnu.2025.06.005 PubMed
[3] Shreya Verma et al.. J Nutr. 2025. Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. doi:10.1016/j.tjnut.2025.08.029 PubMed
[4] Friederike Wylenzek et al.. Arch Gynecol Obstet. 2024. A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … doi:10.1007/s00404-024-07555-6 PubMed
[5] Jolanta Flieger et al.. Int J Mol Sci. 2024. Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. doi:10.3390/ijms25168982 PubMed
[6] Sitong Wan et al.. Nutrients. 2024. Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. doi:10.3390/nu16142213 PubMed
[7] Michael A Grandner et al.. J Sleep Res. 2014. Sleep symptoms associated with intake of specific dietary nutrients. doi:10.1111/jsr.12084 PubMed
[8] Graziano Riccioni. Curr Atheroscler Rep. 2009. Carotenoids and cardiovascular disease. doi:10.1007/s11883-009-0065-z PubMed

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.

Lycopene per Atherosclerosis

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In sintesi

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Dosaggi di uso comune

Dosaggi studiati nella ricerca

Safety & Side Effects

Effetti collaterali segnalati

Interazioni note

Frequently Asked Questions

Related Evidence

Altri ingredienti per Atherosclerosis

Lycopene per altre condizioni

References