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PQQ (Pyrroloquinoline Quinone)
PQQ (Pyrroloquinoline Quinone)

coenzyme

别名: Pyrroloquinoline Quinone, BioPQQ, Methoxatin

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About





            

                
PQQ is a redox cofactor that stimulates mitochondrial biogenesis and acts as an exceptionally potent antioxidant (5,000 catalytic cycles vs. 4 for vitamin C). A small RCT found PQQ at 20 mg/day significantly reduced LDL cholesterol and CRP, but larger cardiovascular-specific human trials are needed.

            

        

        

        
        
        

            

  
How It Works





            

                
Redox cofactor that stimulates mitochondrial biogenesis through PGC-1alpha/SIRT1/AMPK signaling pathways; acts as an exceptionally potent antioxidant protecting mitochondrial membranes and reducing oxidative stress-induced endothelial damage; supports NAD+ synthesis indirectly by enhancing cellular energy metabolism; modulates NF-kB reducing vascular inflammation.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Oxidative Stress (Cardiovascular)
                                    
                                
                                
                                    C

                                
                                
                                    2
                                
                                
                                    100
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Heart Failure
                                    
                                
                                
                                    D

                                
                                
                                    0
                                
                                
                                    --
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Generally well-tolerated
                
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                    Mild headache (rare)
                
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                    Mild gastrointestinal discomfort (rare)
                
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Drug & Supplement Interactions





            
    
                
                
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                    May enhance effects of CoQ10 (synergistic mitochondrial support)
                
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                    Theoretical interaction with anticoagulants
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Coenzyme Q10 (CoQ10)
                    
                
                
                
                    NMN (Nicotinamide Mononucleotide)
                    
                
                
            

        

        
    


    
    












    

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