Skip to main content
HeartCited

PQQ (Pyrroloquinoline Quinone) 用于 氧化应激（心血管）

C 证据 来自小型研究的证据有限，但存在一些积极信号。

Small RCT showed LDL and CRP reduction. Exceptional antioxidant potency. Cardiovascular-specific human data is very limited despite strong preclinical evidence.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'heartcited.com'; const params = 'ingredient\u003Dpqq\u0026condition\u003Doxidative\u002Dstress\u002Dcardiovascular'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  




    








    

        

            C

        

        

            
结论

            
            
Small RCT showed LDL and CRP reduction. Exceptional antioxidant potency. Cardiovascular-specific human data is very limited despite strong preclinical evidence.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Nutraceutical activation of Sirt1: a review.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Sirt1 activation and healthspan
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: General/aging population

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
研究数量

    

    

        
100

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Nutraceutical activation of Sirt1: a review.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Open heart
                        2022
                        
                        52 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
10-20 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
20 mg/day

                    

                    
                

                
                

                    上限： Not formally established; up to 60 mg/day used in short-term studies
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： With or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild headache (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort (rare)
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            May enhance effects of CoQ10 (synergistic mitochondrial support)
                        
    • 
                        
                        
  • 
                            ●
                            Theoretical interaction with anticoagulants
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not formally established; up to 60 mg/day used in short-term studies
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does PQQ (Pyrroloquinoline Quinone) help with 氧化应激（心血管）?
            
        
        

            Based on 2 studies with 100 participants, there is limited but promising evidence that PQQ (Pyrroloquinoline Quinone) may support 氧化应激（心血管） management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much PQQ (Pyrroloquinoline Quinone) should I take for 氧化应激（心血管）?
            
        
        

            Studies have used various dosages. A commonly studied range is 10-20 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of PQQ (Pyrroloquinoline Quinone)?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild headache (rare), Mild gastrointestinal discomfort (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for PQQ (Pyrroloquinoline Quinone) and 氧化应激（心血管）?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
其他成分用于 氧化应激（心血管）

                    

                        
                        
                            Selenium
                            B

                        
                        
                    

                

                

                
                

                    
PQQ (Pyrroloquinoline Quinone) 用于其他健康状况

                    

                        
                        
                            心力衰竭
                            D

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      James J DiNicolantonio et al..
      Open Heart.
      2022.
      Nutraceutical activation of Sirt1: a review.
      doi:10.1136/openhrt-2022-002171
      PubMed
    
    2. 
    
  















    

        FDA 免责声明:
        这些声明未经美国食品药品监督管理局（FDA）评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析，不构成医疗建议。在开始任何补充剂方案之前，请务必咨询您的医疗保健提供者。