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Hawthorn para Heart Failure

B

Cochrane review of 14 RCTs: improved exercise tolerance and symptom scores. SPICE trial (2,681 patients) showed trend toward benefit. German Commission E-approved for declining cardiac function (NYHA I-II).

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B

Conclusão

Cochrane review of 14 RCTs: improved exercise tolerance and symptom scores. SPICE trial (2,681 patients) showed trend toward benefit. German Commission E-approved for declining cardiac function (NYHA I-II).

Key Statistics

14

Estudos

3800

Participantes

Positive

B

Nota

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:
450-900 mg/day standardized extract (WS 1442 or LI 132)
standardization:
18.75% OPCs or 2.2% flavonoids

Limite superior: Not formally established; up to 1,800 mg/day used in the SPICE trial

Melhor horário: With meals; effects require 6-8 weeks of continuous use

Safety & Side Effects

Efeitos Colaterais Relatados

  • Generally well-tolerated
  • Dizziness
  • Nausea
  • Gastrointestinal discomfort
  • Headache

Interações Conhecidas

  • Cardiac glycosides (digoxin — may enhance inotropic effects)
  • Antihypertensives (additive blood pressure lowering)
  • Beta-blockers (additive cardiac effects)
  • PDE5 inhibitors (additive vasodilation)

Ingestão máxima tolerável: Not formally established; up to 1,800 mg/day used in the SPICE trial

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Hawthorn help with Heart Failure?
Based on 14 studies with 3,800 participants, there is moderate evidence from clinical studies that Hawthorn may support Heart Failure management. Our evidence grade is B (Good Evidence).
How much Hawthorn should I take for Heart Failure?
Studies have used various dosages. A commonly studied range is 450-900 mg/day standardized extract (WS 1442 or LI 132). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Hawthorn?
Reported side effects may include Generally well-tolerated, Dizziness, Nausea, Gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Hawthorn and Heart Failure?
We rate the evidence as Grade B (Good Evidence). This rating is based on 14 peer-reviewed studies with 3,800 total participants. The overall direction of effect is positive.

Related Evidence

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.