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HeartCited

Taurine para Heart Failure

C Evidências Evidência limitada de estudos de pequena dimensão, mas existem alguns sinais positivos.

Small RCTs show improved exercise capacity and cardiac function. Mechanistically compelling as the most abundant free amino acid in the heart. Larger trials are needed.

C

Conclusão

Small RCTs show improved exercise capacity and cardiac function. Mechanistically compelling as the most abundant free amino acid in the heart. Larger trials are needed.

Key Study Findings

Other n=25 4 weeks
Effect of probiotic administration of Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 …
Dose: Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 vs: phosphate-buffered saline (PBS) Outcome: visceral hypersensitivity (abdominal withdrawal reflex scores) p<0.05

População: female rats with water avoidance stress-induced IBS-D model

Other
Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine …
Dose: 50 mg/kg lycopene in mice vs: HFD control mice Outcome: Cognitive function (Y-maze, MWM, novel object recognition)

População: HFD-induced obese male C57BL/6 mice

Controlled Clinical Trial 6 weeks
Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac …
Dose: 400 mg/kg/day vs: ROFA exposure without taurine Outcome: Multi-organ oxidative stress and neuroinflammation

População: Male Wistar rats with intranasal ROFA exposure

Key Statistics

4

Estudos

200

Participantes

↑

Positive

C

Nota

Referenced Papers

Effect of probiotic administration of Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 on metabolic profiles in an … Other
Journal of the … 2026
Natural sulfur compounds in mental health and neurological disorders: insights from observational and intervention studies. Review
Frontiers in nutrition 2025 7 citações
Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. Other
Clinical nutrition (Edinburgh, … 2025 1 citações
Transcriptomics study of hippocampus in mice exposed to heat stress. Other
Psychoneuroendocrinology 2025 1 citações
Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac tissues and promotes neuroinflammation, with … Other
Neurotoxicology 2025
Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors. Other
PloS one 2024 5 citações
Neuroinflammatory and Neurometabolomic Consequences From Inhaled Wildfire Smoke-Derived Particulate Matter in the Western United States. Other
Toxicological sciences : … 2022 29 citações
Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation. Other
Journal of proteome … 2006 80 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:
1,000-3,000 mg/day
heartfailuresupport:
2,000-3,000 mg/day
bloodpressuresupport:
1,500-3,000 mg/day

Limite superior: EFSA considers 6,000 mg/day safe; up to 6,000 mg/day used in clinical trials

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 4 weeks Positive 25
50 mg/kg lycopene in mice -- Positive --
400 mg/kg/day 6 weeks Mixed --

Melhor horário: Can be taken with or without food; divide doses >2,000 mg

Safety & Side Effects

Efeitos Colaterais Relatados

  • ⚠ Generally well-tolerated even at high doses
  • ⚠ Mild gastrointestinal discomfort (rare)
  • ⚠ Drowsiness (mild, at high doses)

Interações Conhecidas

  • ● Antihypertensives (additive blood pressure lowering)
  • ● Lithium (may alter lithium excretion)
  • ● Antiepileptic drugs (may modulate GABA activity)

Ingestão máxima tolerável: EFSA considers 6,000 mg/day safe; up to 6,000 mg/day used in clinical trials

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Taurine help with Heart Failure?
Based on 4 studies with 200 participants, there is limited but promising evidence that Taurine may support Heart Failure management. Our evidence grade is C (Some Evidence).
How much Taurine should I take for Heart Failure?
Studies have used various dosages. A commonly studied range is 1,000-3,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Taurine?
Reported side effects may include Generally well-tolerated even at high doses, Mild gastrointestinal discomfort (rare), Drowsiness (mild, at high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Taurine and Heart Failure?
We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.

Taurine para outras condições

High Blood Pressure (Hypertension) B

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References

  
    
    
    
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      [1]
      Nazila Dardmeh et al..
      J Sci Food Agric.
      2026.
      Effect of probiotic administration of Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 on metabolic profiles in an …
      doi:10.1002/jsfa.70190
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Apeksha Rana et al..
      Front Nutr.
      2025.
      Natural sulfur compounds in mental health and neurological disorders: insights from observational and intervention studies.
      doi:10.3389/fnut.2025.1534000
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Yuqing Wu et al..
      Clin Nutr.
      2025.
      Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway.
      doi:10.1016/j.clnu.2025.06.005
      PubMed
    
    4. 
    
    
  4. 
      [4]
      Bin Li et al..
      Psychoneuroendocrinology.
      2025.
      Transcriptomics study of hippocampus in mice exposed to heat stress.
      doi:10.1016/j.psyneuen.2025.107279
      PubMed
    
    5. 
    
    
  5. 
      [5]
      Gedaias Noronha da Silva et al..
      Neurotoxicology.
      2025.
      Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac tissues and promotes neuroinflammation, with …
      doi:10.1016/j.neuro.2025.103347
      PubMed
    
    6. 
    
    
  6. 
      [6]
      Williams Kobik et al..
      PLoS One.
      2024.
      Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors.
      doi:10.1371/journal.pone.0289391
      PubMed
    
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  7. 
      [7]
      David Scieszka et al..
      Toxicol Sci.
      2022.
      Neuroinflammatory and Neurometabolomic Consequences From Inhaled Wildfire Smoke-Derived Particulate Matter in the Western United States.
      doi:10.1093/toxsci/kfab147
      PubMed
    
    8. 
    
    
  8. 
      [8]
      Francois-Pierre J Martin et al..
      J Proteome Res.
      2006.
      Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation.
      doi:10.1021/pr060157b
      PubMed
    
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        Aviso Legal da FDA:
        Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.