What is the recommended dosage for Hawthorn?

General: 450-900 mg/day standardized extract (WS 1442 or LI 132); Standardization: 18.75% OPCs or 2.2% flavonoids

What are the side effects of Hawthorn?

Potential side effects include: Generally well-tolerated, Dizziness, Nausea, Gastrointestinal discomfort, Headache.

What is hawthorn and how may it support cardiovascular health?

Hawthorn (Crataegus) has been used for centuries in traditional medicine for heart conditions. It contains flavonoids and oligomeric proanthocyanidins that may improve coronary blood flow, increase cardiac contractility, and reduce blood pressure. Several European trials showed benefits for mild heart failure symptoms.

What dosage of hawthorn has been studied in cardiovascular trials?

Clinical studies have used 160–1,800 mg per day of hawthorn leaf and flower extract standardized to 2.2% flavonoids or 18.75% OPCs. The SPICE trial used WS 1442 extract at 900 mg daily for 24 months in heart failure patients. Lower doses of 160–480 mg daily are used for milder cardiovascular support.

What are the potential side effects of hawthorn?

Hawthorn is generally well tolerated. Mild side effects include dizziness, nausea, and digestive discomfort. It may enhance the effects of cardiac glycosides (digoxin), blood pressure medications, and vasodilators. Individuals taking heart medications should consult a cardiologist before using hawthorn.

Hawthorn
Hawthorn

herb

Também conhecido como: Crataegus, Crataegus monogyna, Crataegus laevigata, Hawthorne, Whitethorn

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About

Hawthorn berry/leaf/flower extract contains OPCs and flavonoids that improve cardiac contractile force without increasing oxygen demand. A 2008 Cochrane review of 14 RCTs (1,110 heart failure patients) found hawthorn significantly improved exercise tolerance and reduced dyspnea. Hawthorn is approved by the German Commission E for declining cardiac function (NYHA I-II).

How It Works

Oligomeric procyanidins and flavonoids inhibit phosphodiesterase-3 (PDE3) increasing cardiac cAMP and improving contractile force (positive inotropic effect without increasing oxygen demand); enhances coronary artery blood flow via endothelium-dependent vasodilation; reduces peripheral vascular resistance; antioxidant flavonoids protect against myocardial ischemia-reperfusion injury; mild ACE-inhibitory activity.

Evidence For Conditions

Condição	Nota	Estudos	Participantes
Heart Failure	B	14	3800	Ver →
High Blood Pressure (Hypertension)	C	4	300	Ver →

Side Effects

Generally well-tolerated
Dizziness
Nausea
Gastrointestinal discomfort
Headache

Drug & Supplement Interactions

Cardiac glycosides (digoxin — may enhance inotropic effects)
Antihypertensives (additive blood pressure lowering)
Beta-blockers (additive cardiac effects)
PDE5 inhibitors (additive vasodilation)

Informe sempre o seu profissional de saúde sobre todos os suplementos que você toma.Sempre informe seu profissional de saúde sobre todos os suplementos que você toma.

Related Ingredients

Garlic Curcumin Berberine Red Yeast Rice

Dados Rápidos

Dosagem: General: 450-900 mg/day standardized extract (WS 1442 or LI 132); Standardization: 18.75% OPCs or 2.2% flavonoids
Formas: capsule tablet liquid tincture dried berry tea
Fontes Naturais: Hawthorn berries, leaves, and flowers (Crataegus species)
Limite Superior: Not formally established; up to 1,800 mg/day used in the SPICE trial
Melhor Horário: With meals; effects require 6-8 weeks of continuous use

Resumo das Evidências

Heart Failure B

High Blood Pressure (Hypertension) C

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.