MagnesiumMagnesium
mineral
다른 이름: Magnesium Glycinate, Magnesium Citrate, Magnesium Taurate, Magnesium L-Threonate, Magnesium Oxide
About
Magnesium is an essential cofactor for over 300 enzymatic reactions including those regulating vascular tone. It acts as a natural calcium channel blocker, relaxing vascular smooth muscle and reducing peripheral resistance. A 2016 meta-analysis of 34 RCTs found magnesium supplementation significantly reduced systolic blood pressure by 2.0 mmHg and diastolic by 1.78 mmHg. Approximately 50% of the US population consumes less than the EAR for magnesium.
How It Works
Essential cofactor for >300 enzymatic reactions regulating vascular tone; acts as a natural calcium channel blocker relaxing vascular smooth muscle; modulates cardiac electrical activity by stabilizing potassium and calcium channels (anti-arrhythmic); supports endothelial nitric oxide production; regulates Na+/K+-ATPase critical for cardiac membrane potential.
Evidence For Conditions
| 건강 상태 | 등급 | 연구 | 참여자 | |
|---|---|---|---|---|
| High Blood Pressure (Hypertension) | B | 34 | 2028 | 보기 → |
| Cardiac Arrhythmia | B | 8 | 500 | 보기 → |
| Coronary Artery Disease (CAD) | C | 5 | 350 | 보기 → |
Side Effects
- Diarrhea (especially magnesium oxide and citrate)
- Nausea
- Abdominal cramping
- Excessive doses may cause hypotension or cardiac depression
Drug & Supplement Interactions
- Bisphosphonates (reduced absorption — separate by 2 hours)
- Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
- Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
- Proton pump inhibitors (long-term use may cause hypomagnesemia)
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Related Ingredients
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