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HeartCited

Resveratrol untuk Atherosclerosis

C

Improves FMD and reduces inflammatory markers. RESVACE trial was negative for cardiac function in heart failure. Bioavailability challenges limit clinical translation.

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C

Kesimpulan

Improves FMD and reduces inflammatory markers. RESVACE trial was negative for cardiac function in heart failure. Bioavailability challenges limit clinical translation.

Key Statistics

5

Studi

400

Peserta

Positive

C

Peringkat

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
150-500 mg/day
cardiovascularsupport:
250-500 mg/day trans-resveratrol

Batas atas: Not formally established; GI discomfort common above 1,000 mg/day

Waktu terbaik diminum: With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
  • Headache
  • May have estrogenic activity at high doses

Interaksi yang Diketahui

  • Anticoagulants (may inhibit platelet aggregation)
  • CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
  • Blood pressure medications (additive hypotensive effect)
  • Estrogen-sensitive conditions (weak estrogenic activity)

Asupan atas yang dapat ditoleransi: Not formally established; GI discomfort common above 1,000 mg/day

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Resveratrol help with Atherosclerosis?
Based on 5 studies with 400 participants, there is limited but promising evidence that Resveratrol may support Atherosclerosis management. Our evidence grade is C (Some Evidence).
How much Resveratrol should I take for Atherosclerosis?
Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and Atherosclerosis?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Related Evidence

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.