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Grape Seed Extract untuk Endothelial Dysfunction

C

Improved FMD in several small RCTs. OPCs have 20-50x antioxidant capacity vs. vitamins C and E. Larger trials with clinical endpoints are needed.

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C

Kesimpulan

Improved FMD in several small RCTs. OPCs have 20-50x antioxidant capacity vs. vitamins C and E. Larger trials with clinical endpoints are needed.

Key Statistics

6

Studi

350

Peserta

Positive

C

Peringkat

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
100-300 mg/day
bloodpressuresupport:
150-300 mg/day standardized to 95% OPCs

Batas atas: Not formally established; up to 600 mg/day used in clinical trials

Waktu terbaik diminum: With or without food

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Generally well-tolerated
  • Mild headache (rare)
  • Dizziness (rare)
  • Nausea (rare)

Interaksi yang Diketahui

  • Anticoagulants (may increase bleeding risk)
  • Blood pressure medications (additive hypotensive effect)
  • Iron supplements (tannins may reduce iron absorption)

Asupan atas yang dapat ditoleransi: Not formally established; up to 600 mg/day used in clinical trials

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Grape Seed Extract help with Endothelial Dysfunction?
Based on 6 studies with 350 participants, there is limited but promising evidence that Grape Seed Extract may support Endothelial Dysfunction management. Our evidence grade is C (Some Evidence).
How much Grape Seed Extract should I take for Endothelial Dysfunction?
Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Grape Seed Extract?
Reported side effects may include Generally well-tolerated, Mild headache (rare), Dizziness (rare), Nausea (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Grape Seed Extract and Endothelial Dysfunction?
We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.

Related Evidence

Bahan lain untuk Endothelial Dysfunction

Grape Seed Extract untuk kondisi lain

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.