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Astaxanthin untuk Endothelial Dysfunction

D Penelitian Hanya penelitian awal yang ada (studi laboratorium, laporan kasus).

Improved blood rheology and microcirculation in small RCTs. Membrane-spanning antioxidant may help protect endothelial cells. FMD endpoint studies are needed.

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Kesimpulan

            
            
Improved blood rheology and microcirculation in small RCTs. Membrane-spanning antioxidant may help protect endothelial cells. FMD endpoint studies are needed.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Astaxanthin: a novel potential treatment for oxidative stress …
                
                
                Efek: None
                
                
                None
                
            

            
            
Populasi: None

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
Studi

    

    

        
100

        
Peserta

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
Peringkat

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        The American journal …
                        2008
                        
                        441 sitasi
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosis yang Umum Digunakan

                

                    
                    

                        
general:

                        
4-12 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
8-12 mg/day

                    

                    
                

                
                

                    Batas atas: Not formally established; up to 40 mg/day used in short-term studies
                

                
            

            

            
            

                
Dosis yang Diteliti dalam Penelitian

                

                    

                        
                            

                                Dosis
                                Durasi
                                Efek
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Waktu terbaik diminum: With meals containing fat (carotenoid — fat-soluble)
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Efek Samping yang Dilaporkan

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Orange skin discoloration at very high doses (harmless)
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                    

                

                

                
                

                    
Interaksi yang Diketahui

                    
    
                        
                        
  • 
                            ●
                            Blood pressure medications (may have mild additive hypotensive effect)
                        
    • 
                        
                        
  • 
                            ●
                            Hormone-sensitive conditions (theoretical, as carotenoid)
                        
    • 
                        
                    

                

                

                
                

                    

                        Asupan atas yang dapat ditoleransi: Not formally established; up to 40 mg/day used in short-term studies
                    

                

                
            

            

                Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Astaxanthin help with Endothelial Dysfunction?
            
        
        

            Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Astaxanthin may support Endothelial Dysfunction management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Astaxanthin should I take for Endothelial Dysfunction?
            
        
        

            Studies have used various dosages. A commonly studied range is 4-12 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Astaxanthin?
            
        
        

            Reported side effects may include Generally well-tolerated, Orange skin discoloration at very high doses (harmless), Mild gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Astaxanthin and Endothelial Dysfunction?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
Bahan lain untuk Endothelial Dysfunction

                    

                        
                        
                            Cocoa Flavanols
                            A

                        
                        
                        
                            L-Arginine
                            C

                        
                        
                        
                            Grape Seed Extract
                            C

                        
                        
                    

                

                

                
                

                    
Astaxanthin untuk kondisi lain

                    

                        
                        
                            High Cholesterol (Hyperlipidemia)
                            C

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Fredric J Pashkow et al..
      Am J Cardiol.
      2008.
      Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease.
      doi:10.1016/j.amjcard.2008.02.010
      PubMed
    
    2. 
    
  















    

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