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Grape Seed Extract para Endothelial Dysfunction

C

Improved FMD in several small RCTs. OPCs have 20-50x antioxidant capacity vs. vitamins C and E. Larger trials with clinical endpoints are needed.

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C

Conclusión

Improved FMD in several small RCTs. OPCs have 20-50x antioxidant capacity vs. vitamins C and E. Larger trials with clinical endpoints are needed.

Key Statistics

6

Estudios

350

Participantes

Positive

C

Calificación

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

general:
100-300 mg/day
bloodpressuresupport:
150-300 mg/day standardized to 95% OPCs

Límite superior: Not formally established; up to 600 mg/day used in clinical trials

Mejor momento para tomar: With or without food

Safety & Side Effects

Efectos secundarios reportados

  • Generally well-tolerated
  • Mild headache (rare)
  • Dizziness (rare)
  • Nausea (rare)

Interacciones conocidas

  • Anticoagulants (may increase bleeding risk)
  • Blood pressure medications (additive hypotensive effect)
  • Iron supplements (tannins may reduce iron absorption)

Ingesta máxima tolerable: Not formally established; up to 600 mg/day used in clinical trials

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Grape Seed Extract help with Endothelial Dysfunction?
Based on 6 studies with 350 participants, there is limited but promising evidence that Grape Seed Extract may support Endothelial Dysfunction management. Our evidence grade is C (Some Evidence).
How much Grape Seed Extract should I take for Endothelial Dysfunction?
Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Grape Seed Extract?
Reported side effects may include Generally well-tolerated, Mild headache (rare), Dizziness (rare), Nausea (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Grape Seed Extract and Endothelial Dysfunction?
We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.

Related Evidence

Otros ingredientes para Endothelial Dysfunction

Grape Seed Extract para otras condiciones

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.