Skip to main content
HeartCited

Grape Seed Extract para Endothelial Dysfunction

C Evidencia Evidencia limitada de estudios pequeños, pero existen algunas señales positivas.

Improved FMD in several small RCTs. OPCs have 20-50x antioxidant capacity vs. vitamins C and E. Larger trials with clinical endpoints are needed.

C

Conclusión

Improved FMD in several small RCTs. OPCs have 20-50x antioxidant capacity vs. vitamins C and E. Larger trials with clinical endpoints are needed.

Key Study Findings

Randomized Controlled Trial 8 weeks Double-blind
Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers …
Dose: 180 mg/d Outcome: lipid levels p < 0.001

Población: Patients with dyslipidemia

Key Statistics

6

Estudios

350

Participantes

↑

Positive

C

Calificación

Referenced Papers

Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with … RCT
Nutrients 2023 8 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

general:
100-300 mg/day
bloodpressuresupport:
150-300 mg/day standardized to 95% OPCs

Límite superior: Not formally established; up to 600 mg/day used in clinical trials

Dosificaciones estudiadas en la investigación

Dosificación Duración Efecto N
180 mg/d 8 weeks Positive --

Mejor momento para tomar: With or without food

Safety & Side Effects

Efectos secundarios reportados

  • ⚠ Generally well-tolerated
  • ⚠ Mild headache (rare)
  • ⚠ Dizziness (rare)
  • ⚠ Nausea (rare)

Interacciones conocidas

  • ● Anticoagulants (may increase bleeding risk)
  • ● Blood pressure medications (additive hypotensive effect)
  • ● Iron supplements (tannins may reduce iron absorption)

Ingesta máxima tolerable: Not formally established; up to 600 mg/day used in clinical trials

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Grape Seed Extract help with Endothelial Dysfunction?
Based on 6 studies with 350 participants, there is limited but promising evidence that Grape Seed Extract may support Endothelial Dysfunction management. Our evidence grade is C (Some Evidence).
How much Grape Seed Extract should I take for Endothelial Dysfunction?
Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Grape Seed Extract?
Reported side effects may include Generally well-tolerated, Mild headache (rare), Dizziness (rare), Nausea (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Grape Seed Extract and Endothelial Dysfunction?
We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.

Otros ingredientes para Endothelial Dysfunction

Cocoa Flavanols A L-Arginine C Astaxanthin D

Grape Seed Extract para otras condiciones

High Blood Pressure (Hypertension) B

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  










  
References

  
    
    
    
  1. 
      [1]
      Nicholas Angelopoulos et al..
      Nutrients.
      2023.
      Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with …
      doi:10.3390/nu15122682
      PubMed
    
    2. 
    
  















    

        Aviso legal FDA:
        Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.