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Resveratrol के लिए High Blood Pressure (Hypertension)

B संबंधित साक्ष्य कम से कम एक यादृच्छिक परीक्षण इसका समर्थन करता है, जिसके परिणाम अधिकतर सुसंगत हैं।

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

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B

निष्कर्ष

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Key Study Findings

Review
Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk.
Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: review of nutrition and lifestyle interventions for dyslipidemia and cardiometabolic risk

Review
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.
Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: review of age-related cardiac dysfunction and heart failure mechanisms

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily बनाम: Placebo Outcome: Preeclampsia risk reduction प्रभाव: ~50% risk reduction None

जनसंख्या: Pregnant women with low calcium intake

Systematic Review
The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.
Dose: None बनाम: Placebo or no treatment Outcome: Cardiometabolic changes in menopausal women प्रभाव: None None

जनसंख्या: Menopausal women

Controlled Clinical Trial
Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway.
Dose: None बनाम: Model group (no RES) and sham control Outcome: Cerebral aneurysm formation प्रभाव: None P<0.05

जनसंख्या: Mice with induced hypertension CA model

Review
The Role of Resveratrol Administration in Human Obesity.
Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: Obese adults

Key Statistics

10

अध्ययन

600

प्रतिभागी

Positive

B

ग्रेड

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

general:
150-500 mg/day
cardiovascularsupport:
250-500 mg/day trans-resveratrol

अधिकतम सीमा: Not formally established; GI discomfort common above 1,000 mg/day

अनुसंधान में अध्ययन की गई खुराकें

खुराक अवधि प्रभाव N
None -- Positive --
None -- Neutral --
500 mg daily -- Positive --
None -- Positive --
None -- Positive --
None -- Mixed --
75 mg 14 weeks Positive 129
None -- Mixed --

सेवन का सर्वोत्तम समय: With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

  • Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
  • Headache
  • May have estrogenic activity at high doses

ज्ञात अंतःक्रियाएँ

  • Anticoagulants (may inhibit platelet aggregation)
  • CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
  • Blood pressure medications (additive hypotensive effect)
  • Estrogen-sensitive conditions (weak estrogenic activity)

सहनीय अधिकतम सेवन: Not formally established; GI discomfort common above 1,000 mg/day

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Resveratrol help with High Blood Pressure (Hypertension)?
Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Resveratrol should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

इसके लिए अन्य सामग्री High Blood Pressure (Hypertension)

Resveratrol अन्य स्वास्थ्य स्थितियों के लिए

References

  1. [1] Zhuyubing Fang et al.. ESC Heart Fail. 2025. Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. doi:10.1002/ehf2.14947 PubMed
  2. [2] Hygerta Berisha et al.. Nutrients. 2025. Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. doi:10.3390/nu17050776 PubMed
  3. [3] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
  4. [4] Ali Amini et al.. Cardiovasc Hematol Disord Drug Targets. 2025. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. doi:10.2174/011871529X398468250910225946 PubMed
  5. [5] Tao Jin et al.. Acta Biochim Pol. 2022. Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. doi:10.18388/abp.2020_5982 PubMed
  6. [6] Laura M Mongioì et al.. Int J Mol Sci. 2021. The Role of Resveratrol Administration in Human Obesity. doi:10.3390/ijms22094362 PubMed
  7. [7] Jay Jay Thaung Zaw et al.. Nutrients. 2020. Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. doi:10.3390/nu12030828 PubMed
  8. [8] Raúl Francisco Pastor et al.. Nutrients. 2020. Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. doi:10.3390/nu12103149 PubMed
  9. [9] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।