Evidenzbasierte Nahrungsergänzungsmittel-Bewertungen
Every heart claim cited.
We read the cardiovascular studies so you don't have to.
Evidence-based supplement research you can trust. We analyze peer-reviewed clinical studies from PubMed and grade every supplement ingredient on a transparent A–D scale. No sponsored rankings, no manufacturer influence — just science.
Featured Ingredients
Coenzyme Q10 (CoQ10)
coenzymeEssential cofactor in mitochondrial electron transport chain (Complex I-III) supporting cellular energy production (ATP) in high-demand cardiac tissue; potent lipid-soluble …
Vitamin D
vitaminBinds to vitamin D receptors (VDR) on cardiomyocytes, vascular smooth muscle, and endothelial cells regulating calcium handling and contractile function; …
Vitamin K2
vitaminActivates matrix Gla protein (MGP) — the most potent natural inhibitor of arterial calcification — through gamma-carboxylation; directs calcium deposition …
Niacin (Vitamin B3)
vitaminActivates GPR109A (HCA2) receptor in adipocytes reducing lipolysis and free fatty acid flux to the liver, decreasing hepatic VLDL/triglyceride production; …
Magnesium
mineralEssential cofactor for >300 enzymatic reactions regulating vascular tone; acts as a natural calcium channel blocker relaxing vascular smooth muscle; …
Omega-3 Fatty Acids (EPA/DHA)
fatty_acidLong-chain polyunsaturated fatty acids that incorporate into cell membranes modulating inflammatory signaling via reduced arachidonic acid conversion to pro-inflammatory eicosanoids; …
Top Conditions
High Cholesterol (Hyperlipidemia)
38% of US adults have total cholesterol >=200 mg/dL; 12% have LDL >=160 mg/dL
Atherosclerosis
Subclinical atherosclerosis present in >50% of adults over 40
Heart Failure
6.7 million US adults; prevalence increases with age (10% in adults >65)
Cardiac Arrhythmia
Atrial fibrillation: 33.5 million worldwide; PVCs: present in 75% of healthy adults
Peripheral Artery Disease (PAD)
8.5 million US adults; 12-20% of adults >60 years
High Blood Pressure (Hypertension)
47% of US adults (116 million); ~1.28 billion adults worldwide
Recent Evidence Updates
6 Studien
3 Studien
5 Studien
11 Studien
12 Studien
Guides & Resources
Exercise for Heart Health: How Supplements Can Support Your Routine
Regular physical activity is unequivocally one of the most powerful interventions for cardiovascular health, with effects that rival or exceed many pharmaceutical treatments. The American …
lifestyleThe Mediterranean Diet and Heart Supplements: A Complete Guide
The Mediterranean diet stands as the most well-validated dietary pattern for cardiovascular disease prevention, supported by decades of epidemiological evidence and confirmed by the landmark …
safetyTaking Supplements While on Blood Thinners: Essential Cautions
Anticoagulant and antiplatelet medications — including warfarin, heparin, direct oral anticoagulants (DOACs such as apixaban, rivaroxaban, edoxaban, and dabigatran), aspirin, clopidogrel, and prasugrel — are …
Evidence Grading System
Every supplement claim on this site is graded on an A–D scale based on peer-reviewed clinical research from PubMed. Our algorithm evaluates study design (RCTs rank highest), consistency of results, sample sizes, and the overall body of evidence. No manufacturer sponsorship influences our grades.
Multiple randomized controlled trials (RCTs) or meta-analyses with consistent positive results and large sample sizes.
At least one RCT with mostly consistent results across studies. Evidence suggests benefit but more research may be needed.
Small studies or observational data with some positive signals. Promising but insufficient for strong recommendations.
In vitro studies, case reports, or pilot studies only. Early-stage research that requires clinical validation.
How It Works
Keine Werbung. Keine gesponserten Rankings. Nur Wissenschaft.
Forschungszentrum
Wir durchsuchen PubMed nach jeder klinischen Studie zu Nahrungsergänzungs-Inhaltsstoffen.
Extraktion
Wir extrahieren die wichtigsten Erkenntnisse — Stichprobengrößen, Studientypen und Ergebnisse.
Grade A bis F
Wir bewerten die Evidenz wie ein Schulzeugnis — von A (stark) bis F (negativ).
Klare Antwort
Sie erhalten in Sekunden eine klare Antwort — wirkt dieses Nahrungsergänzungsmittel tatsächlich?
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FDA-Haftungsausschluss: Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.