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Curcumin
Curcumin

herb

别名: Turmeric Extract, Curcuma longa, Diferuloylmethane, Theracurmin, Longvida, Meriva

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About





            

                
Curcumin, the active compound in turmeric, is a potent modulator of vascular inflammation through NF-kB, JAK/STAT, and MAPK pathway inhibition. A 2017 meta-analysis found curcumin significantly reduced total cholesterol, LDL, and triglycerides in metabolic syndrome patients. Enhanced bioavailability formulations (Theracurmin, Longvida, Meriva) provide 25-185x improvements over standard curcumin.

            

        

        

        
        
        

            

  
How It Works





            

                
Potent modulator of vascular inflammation through NF-kB, JAK/STAT, and MAPK pathway inhibition; reduces endothelial expression of adhesion molecules decreasing monocyte recruitment; improves endothelial function by enhancing eNOS expression and nitric oxide bioavailability; reduces ox-LDL uptake by macrophages inhibiting foam cell formation; anti-thrombotic activity via COX-2 inhibition.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Cardiovascular Inflammation
                                    
                                
                                
                                    B

                                
                                
                                    12
                                
                                
                                    1000
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        High Cholesterol (Hyperlipidemia)
                                    
                                
                                
                                    C

                                
                                
                                    7
                                
                                
                                    500
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Gastrointestinal discomfort (nausea, diarrhea)
                
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                    Yellow staining of skin/teeth at high doses
                
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                    May increase gallbladder contractions
                
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                    Headache (rare)
                
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Drug & Supplement Interactions





            
    
                
                
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                    Anticoagulants (may increase bleeding risk)
                
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                    Antiplatelet drugs (additive antiplatelet effect)
                
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                    Diabetes medications (may lower blood sugar)
                
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                    CYP3A4 substrates (may alter metabolism)
                
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                    Iron supplements (curcumin may chelate iron)
                
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Related Ingredients





            

                
                
                    Hawthorn
                    
                
                
                
                    Garlic
                    
                
                
                
                    Berberine
                    
                
                
                
                    Red Yeast Rice
                    
                
                
            

        

        
    


    
    












    

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