Resveratrol için High Blood Pressure (Hypertension)

Q: Does Resveratrol help with High Blood Pressure (Hypertension)?

Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

Q: How much Resveratrol should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Resveratrol?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

B Kanıt Bunu büyük ölçüde tutarlı sonuçlarla en az bir randomize çalışma desteklemektedir.

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

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Sonuç

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Key Study Findings

Review

Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk.

Dose: None vs: None Outcome: None Etki: None None

Popülasyon: review of nutrition and lifestyle interventions for dyslipidemia and cardiometabolic risk

Review

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.

Dose: None vs: None Outcome: None Etki: None None

Popülasyon: review of age-related cardiac dysfunction and heart failure mechanisms

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Etki: ~50% risk reduction None

Popülasyon: Pregnant women with low calcium intake

Systematic Review

The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.

Dose: None vs: Placebo or no treatment Outcome: Cardiometabolic changes in menopausal women Etki: None None

Popülasyon: Menopausal women

Controlled Clinical Trial

Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway.

Dose: None vs: Model group (no RES) and sham control Outcome: Cerebral aneurysm formation Etki: None P<0.05

Popülasyon: Mice with induced hypertension CA model

Review

The Role of Resveratrol Administration in Human Obesity.

Dose: None vs: None Outcome: None Etki: None None

Popülasyon: Obese adults

Key Statistics

Çalışmalar

600

Katılımcılar

↑

Positive

Derece

Referenced Papers

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. Review

ESC heart failure 2025 58 atıf

Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. Review

Nutrients 2025 32 atıf

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 atıf

The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. Other

Cardiovascular & hematological … 2025

Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. Other

Acta biochimica Polonica 2022 10 atıf

The Role of Resveratrol Administration in Human Obesity. Review

International journal of … 2021 50 atıf

Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. Other

Nutrients 2020 49 atıf

Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. Other

Nutrients 2020 16 atıf

Nutritional prevention of cognitive decline and dementia. Review

Acta bio-medica : … 2018 103 atıf

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Yaygın Kullanılan Dozajlar

general:: 150-500 mg/day
cardiovascularsupport:: 250-500 mg/day trans-resveratrol

Üst sınır: Not formally established; GI discomfort common above 1,000 mg/day

Araştırmalarda İncelenen Dozajlar

Dozaj	Süre	Etki	N
None	--	Positive	--
None	--	Neutral	--
500 mg daily	--	Positive	--
None	--	Positive	--
None	--	Positive	--
None	--	Mixed	--
75 mg	14 weeks	Positive	129
None	--	Mixed	--

En iyi alım zamanı: With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

Bildirilen Yan Etkiler

⚠ Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
⚠ Headache
⚠ May have estrogenic activity at high doses

Bilinen Etkileşimler

● Anticoagulants (may inhibit platelet aggregation)
● CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
● Blood pressure medications (additive hypotensive effect)
● Estrogen-sensitive conditions (weak estrogenic activity)

Tolere edilebilir üst alım: Not formally established; GI discomfort common above 1,000 mg/day

Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.

Frequently Asked Questions

Does Resveratrol help with High Blood Pressure (Hypertension)?

Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

How much Resveratrol should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Resveratrol?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Şu durum için diğer içerikler: High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Magnesium B Potassium B Quercetin B Grape Seed Extract B

Resveratrol diğer sağlık durumları için

Atherosclerosis C

Hızlı Değerlendirme

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Evidence Strength72%

High confidence

Çalışma Dağılımı

RCT (0)Meta (0)Other (10)

Alternatifleri Karşılaştır

Bu durum için diğer bileşenlerin nasıl karşılaştırıldığını görün.Diğer içeriklerin bu sağlık durumu için nasıl karşılaştırıldığını görün.

Şu durum için tüm içerikleri görüntüle: High Blood Pressure (Hypertension)

Daha Fazla Bilgi

References

[1] Zhuyubing Fang et al.. ESC Heart Fail. 2025. Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. doi:10.1002/ehf2.14947 PubMed
[2] Hygerta Berisha et al.. Nutrients. 2025. Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. doi:10.3390/nu17050776 PubMed
[3] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[4] Ali Amini et al.. Cardiovasc Hematol Disord Drug Targets. 2025. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. doi:10.2174/011871529X398468250910225946 PubMed
[5] Tao Jin et al.. Acta Biochim Pol. 2022. Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. doi:10.18388/abp.2020_5982 PubMed
[6] Laura M Mongioì et al.. Int J Mol Sci. 2021. The Role of Resveratrol Administration in Human Obesity. doi:10.3390/ijms22094362 PubMed
[7] Jay Jay Thaung Zaw et al.. Nutrients. 2020. Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. doi:10.3390/nu12030828 PubMed
[8] Raúl Francisco Pastor et al.. Nutrients. 2020. Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. doi:10.3390/nu12103149 PubMed
[9] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed

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Resveratrol için High Blood Pressure (Hypertension)

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Sonuç

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Yaygın Kullanılan Dozajlar

Araştırmalarda İncelenen Dozajlar

Safety & Side Effects

Bildirilen Yan Etkiler

Bilinen Etkileşimler

Frequently Asked Questions

Related Evidence

Şu durum için diğer içerikler: High Blood Pressure (Hypertension)

Resveratrol diğer sağlık durumları için

References