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Vitamin D için High Blood Pressure (Hypertension)

C Kanıt Küçük çalışmalardan sınırlı kanıt mevcuttur, ancak bazı olumlu sinyaller bulunmaktadır.

Meta-analyses show modest BP reduction (-2-6 mmHg) in deficient populations only. VITAL trial was negative for cardiovascular endpoints. Research suggests benefits may be limited to correcting deficiency.

C

Sonuç

Meta-analyses show modest BP reduction (-2-6 mmHg) in deficient populations only. VITAL trial was negative for cardiovascular endpoints. Research suggests benefits may be limited to correcting deficiency.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Etki: ~50% risk reduction

Popülasyon: Pregnant women with low calcium intake

Systematic Review
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Dose: Disease-modifying agents (tolvaptan, etc.) vs: Placebo or standard care Outcome: Kidney disease progression

Popülasyon: Patients with ADPKD

Observational Study
Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study.
Dose: 36% Outcome: hair regrowth p < 0.05

Popülasyon: Aa referred to our hospitals between 2018 and 2021

cross-sectional observational study n=103
Sleep status in multiple sclerosis: Role of vitamin D and body mass index.
Dose: not applicable vs: Placebo Etki: 37.87% had poor sleep quality; 33.96% had subthreshold or clinical insomnia; sleep status not signif <0.01 (BDI-ISI and BDI-PSQI co
in vitro study
l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 …
Dose: VD 10 nM; LC 250 µM; combined VD+LC vs: Placebo Etki: VD+LC: 46% ROS reduction vs 26% (VD) and 19% (LC) alone; VD+LC: IL-8 inhibition 36% vs 16% (VD alone

Key Statistics

20

Çalışmalar

30000

Katılımcılar

↔

Mixed

C

Derece

Referenced Papers

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database. Other
Brain and behavior 2026
Dietary supplements and prevention of preeclampsia. Review
Hypertension research : … 2025 10 atıf
Cytomegalovirus (CMV), oxidative stress, and inflammation: implications for immunosenescence and age-related diseases in the MARK-AGE population. Other
Biogerontology 2025
Top studies of 2024 relevant to primary care: From the PEER team. Review
Canadian family physician … 2025
Cardiovascular Risk and Systemic Inflammation in Alopecia Areata: An Observational Case-control Study. Observational
Acta dermatovenerologica Croatica … 2025
Interventions for preventing the progression of autosomal dominant polycystic kidney disease. Systematic Review
The Cochrane database … 2024 1 atıf
Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study. Other
Health science reports 2023 3 atıf
Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants. Observational
Nutrients 2022 14 atıf
Sleep status in multiple sclerosis: Role of vitamin D and body mass index. Other
Current journal of … 2022 11 atıf
Sleep patterns modify the association of 25(OH)D with poor cardiovascular health in pregnant women. Other
Frontiers in nutrition 2022 4 atıf
Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters. Other
Family practice 2022 2 atıf
Vegan Diet Health Benefits in Metabolic Syndrome. Review
Nutrients 2021 113 atıf
l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 Secretion in High Glucose Treated … Other
Journal of the … 2021 23 atıf
Potential of Chlorella as a Dietary Supplement to Promote Human Health. Review
Nutrients 2020 219 atıf
Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid … Other
Medical hypotheses 2016 105 atıf
Nutrient intake, nutritional status, and cognitive function with aging. Review
Annals of the … 2016 89 atıf
Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other
International journal of … 2016 28 atıf
Vitamin D in health and disease: a literature review. Review
British journal of … 2013 156 atıf
Occurrence of milnacipran-associated morbilliform rash and serotonin toxicity. Case Report
The Annals of … 2013
The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and … RCT
Contemporary clinical trials 2012 522 atıf
Vitamin D and autoimmune disease. Review
Acta medica Indonesiana 2007 4 atıf
Intensive session: New approaches to medical issues in long-term care. Review
Journal of the … 2007
Sleep behavior disorders in a large cohort of chinese (Taiwanese) patients maintained by long-term hemodialysis. Other
American journal of … 2006
Endometrial effects during hormone replacement therapy with a sequential oestradiol valerate/cyproterone acetate preparation. RCT
Maturitas 1993

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Yaygın Kullanılan Dozajlar

general:
600-800 IU/day
deficiencycorrection:
4,000-5,000 IU/day (under medical supervision)
cardiovascularsupport:
1,000-2,000 IU/day

Üst sınır: 4,000 IU/day (100 mcg)

Araştırmalarda İncelenen Dozajlar

Dozaj Süre Etki N
500 mg daily -- Positive --
Disease-modifying agents (tolvaptan, etc.) -- Positive --
36% -- Mixed --
not applicable -- Neutral 103
VD 10 nM; LC 250 µM; combined VD+LC -- Positive --

En iyi alım zamanı: With a meal containing fat for better absorption

Safety & Side Effects

Bildirilen Yan Etkiler

  • ⚠ Hypercalcemia at very high doses (fatigue, nausea, kidney stones)
  • ⚠ Constipation
  • ⚠ Generally very safe at recommended doses

Bilinen Etkileşimler

  • ● Thiazide diuretics (may increase hypercalcemia risk)
  • ● Statins (theoretical interaction via CYP enzymes)
  • ● Corticosteroids (may reduce vitamin D absorption)
  • ● Weight loss medications (may reduce absorption of fat-soluble vitamins)

Tolere edilebilir üst alım: 4,000 IU/day (100 mcg)

Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.

Frequently Asked Questions

Does Vitamin D help with High Blood Pressure (Hypertension)?
Based on 20 studies with 30,000 participants, there is limited but promising evidence that Vitamin D may support High Blood Pressure (Hypertension) management. Our evidence grade is C (Some Evidence).
How much Vitamin D should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (fatigue, nausea, kidney stones), Constipation, Generally very safe at recommended doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and High Blood Pressure (Hypertension)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 20 peer-reviewed studies with 30,000 total participants. The overall direction of effect is mixed.

Şu durum için diğer içerikler: High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Magnesium B Potassium B Quercetin B Grape Seed Extract B

Vitamin D diğer sağlık durumları için

Heart Failure C

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