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HeartCited

Vitamin D per Heart Failure

C

D-CURE trial showed no benefit in heart failure patients. EVITA found high-dose D3 did not improve outcomes. Some observational data supports benefit with deficiency correction.

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            C

        

        

            
In sintesi

            
            
D-CURE trial showed no benefit in heart failure patients. EVITA found high-dose D3 did not improve outcomes. Some observational data supports benefit with deficiency correction.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
6

        
Studi

    

    

        
3000

        
Partecipanti

    

    

        
            
            ↔
            
        
        
Mixed

    

    

        C

        
Grado

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
600-800 IU/day

                    

                    
                    

                        
deficiencycorrection:

                        
4,000-5,000 IU/day (under medical supervision)

                    

                    
                    

                        
cardiovascularsupport:

                        
1,000-2,000 IU/day

                    

                    
                

                
                

                    Limite massimo: 4,000 IU/day (100 mcg)
                

                
            

            

            

            
            

                Momento migliore per l'assunzione: With a meal containing fat for better absorption
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Hypercalcemia at very high doses (fatigue, nausea, kidney stones)
                        
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                            ⚠
                            Constipation
                        
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  • 
                            ⚠
                            Generally very safe at recommended doses
                        
    • 
                        
                    

                

                

                
                

                    
Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Thiazide diuretics (may increase hypercalcemia risk)
                        
    • 
                        
                        
  • 
                            ●
                            Statins (theoretical interaction via CYP enzymes)
                        
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  • 
                            ●
                            Corticosteroids (may reduce vitamin D absorption)
                        
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                            ●
                            Weight loss medications (may reduce absorption of fat-soluble vitamins)
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: 4,000 IU/day (100 mcg)
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Vitamin D help with Heart Failure?
            
        
        

            Based on 6 studies with 3,000 participants, there is limited but promising evidence that Vitamin D may support Heart Failure management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Vitamin D should I take for Heart Failure?
            
        
        

            Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Vitamin D?
            
        
        

            Reported side effects may include Hypercalcemia at very high doses (fatigue, nausea, kidney stones), Constipation, Generally very safe at recommended doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Vitamin D and Heart Failure?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 3,000 total participants. The overall direction of effect is mixed.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Vitamin D per altre condizioni

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

        Avvertenza FDA:
        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.