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HeartCited

Taurine

amino_acid

Also known as: 2-Aminoethanesulfonic Acid, Taurine Free Form

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About

Taurine is the most abundant free amino acid in the heart, stabilizing cardiac cell membranes and providing anti-arrhythmic effects. A 2018 meta-analysis of 7 RCTs found taurine at 1,000-6,000 mg/day reduced systolic blood pressure by 3.1 mmHg. A 2023 Science study demonstrated taurine supplementation extended healthy lifespan by 10-12% in animal models, with cardiovascular aging as a key mechanism.

How It Works

Stabilizes cardiac cell membranes by modulating calcium and potassium channel activity providing anti-arrhythmic effects; acts as an osmolyte maintaining cardiomyocyte volume; conjugates bile acids enhancing cholesterol excretion; antioxidant activity through direct scavenging; modulates the RAAS reducing blood pressure; enhances cardiac contractility through calcium sensitization without increasing oxygen demand.

Evidence For Conditions

Condition Grade Studies Participants
High Blood Pressure (Hypertension) B 7 400 View →
Heart Failure C 4 200 View →

Side Effects

  • Generally well-tolerated even at high doses
  • Mild gastrointestinal discomfort (rare)
  • Drowsiness (mild, at high doses)

Drug & Supplement Interactions

  • Antihypertensives (additive blood pressure lowering)
  • Lithium (may alter lithium excretion)
  • Antiepileptic drugs (may modulate GABA activity)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.