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Omega-3 Fatty Acids (EPA/DHA) के लिए Coronary Artery Disease (CAD)

B

REDUCE-IT: 25% MACE reduction with high-dose EPA. Mixed results at lower doses (VITAL, ASCEND). Most beneficial in those with elevated triglycerides. AHA recommends for secondary prevention.

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B

निष्कर्ष

REDUCE-IT: 25% MACE reduction with high-dose EPA. Mixed results at lower doses (VITAL, ASCEND). Most beneficial in those with elevated triglycerides. AHA recommends for secondary prevention.

Key Statistics

20

अध्ययन

50000

प्रतिभागी

Positive

B

ग्रेड

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

general:
1,000 mg combined EPA/DHA per day
triglyceridereduction:
2,000-4,000 mg/day (prescription-grade)

अधिकतम सीमा: 5,000 mg/day combined EPA/DHA (FDA GRAS up to 3,000 mg/day from supplements)

सेवन का सर्वोत्तम समय: With meals containing fat for optimal absorption; divide doses >2,000 mg

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

  • Fishy aftertaste or burping
  • Mild gastrointestinal discomfort
  • Potential increased bleeding time at very high doses
  • May increase atrial fibrillation risk at doses >2g/day

ज्ञात अंतःक्रियाएँ

  • Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
  • Blood pressure medications (additive hypotensive effect)
  • Orlistat (may reduce omega-3 absorption)

सहनीय अधिकतम सेवन: 5,000 mg/day combined EPA/DHA (FDA GRAS up to 3,000 mg/day from supplements)

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Omega-3 Fatty Acids (EPA/DHA) help with Coronary Artery Disease (CAD)?
Based on 20 studies with 50,000 participants, there is moderate evidence from clinical studies that Omega-3 Fatty Acids (EPA/DHA) may support Coronary Artery Disease (CAD) management. Our evidence grade is B (Good Evidence).
How much Omega-3 Fatty Acids (EPA/DHA) should I take for Coronary Artery Disease (CAD)?
Studies have used various dosages. A commonly studied range is 1,000 mg combined EPA/DHA per day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Omega-3 Fatty Acids (EPA/DHA)?
Reported side effects may include Fishy aftertaste or burping, Mild gastrointestinal discomfort, Potential increased bleeding time at very high doses, May increase atrial fibrillation risk at doses >2g/day. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Omega-3 Fatty Acids (EPA/DHA) and Coronary Artery Disease (CAD)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 20 peer-reviewed studies with 50,000 total participants. The overall direction of effect is positive.

Related Evidence

इसके लिए अन्य सामग्री Coronary Artery Disease (CAD)

Omega-3 Fatty Acids (EPA/DHA) अन्य स्वास्थ्य स्थितियों के लिए

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।