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Omega-3 Fatty Acids (EPA/DHA) para Coronary Artery Disease (CAD)

B Evidências Pelo menos um ensaio aleatorizado apoia esta conclusão, com resultados maioritariamente consistentes.

REDUCE-IT: 25% MACE reduction with high-dose EPA. Mixed results at lower doses (VITAL, ASCEND). Most beneficial in those with elevated triglycerides. AHA recommends for secondary prevention.

B

Conclusão

REDUCE-IT: 25% MACE reduction with high-dose EPA. Mixed results at lower doses (VITAL, ASCEND). Most beneficial in those with elevated triglycerides. AHA recommends for secondary prevention.

Key Statistics

20

Estudos

50000

Participantes

↑

Positive

B

Nota

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:
1,000 mg combined EPA/DHA per day
triglyceridereduction:
2,000-4,000 mg/day (prescription-grade)

Limite superior: 5,000 mg/day combined EPA/DHA (FDA GRAS up to 3,000 mg/day from supplements)

Melhor horário: With meals containing fat for optimal absorption; divide doses >2,000 mg

Safety & Side Effects

Efeitos Colaterais Relatados

  • ⚠ Fishy aftertaste or burping
  • ⚠ Mild gastrointestinal discomfort
  • ⚠ Potential increased bleeding time at very high doses
  • ⚠ May increase atrial fibrillation risk at doses >2g/day

Interações Conhecidas

  • ● Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
  • ● Blood pressure medications (additive hypotensive effect)
  • ● Orlistat (may reduce omega-3 absorption)

Ingestão máxima tolerável: 5,000 mg/day combined EPA/DHA (FDA GRAS up to 3,000 mg/day from supplements)

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Omega-3 Fatty Acids (EPA/DHA) help with Coronary Artery Disease (CAD)?
Based on 20 studies with 50,000 participants, there is moderate evidence from clinical studies that Omega-3 Fatty Acids (EPA/DHA) may support Coronary Artery Disease (CAD) management. Our evidence grade is B (Good Evidence).
How much Omega-3 Fatty Acids (EPA/DHA) should I take for Coronary Artery Disease (CAD)?
Studies have used various dosages. A commonly studied range is 1,000 mg combined EPA/DHA per day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Omega-3 Fatty Acids (EPA/DHA)?
Reported side effects may include Fishy aftertaste or burping, Mild gastrointestinal discomfort, Potential increased bleeding time at very high doses, May increase atrial fibrillation risk at doses >2g/day. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Omega-3 Fatty Acids (EPA/DHA) and Coronary Artery Disease (CAD)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 20 peer-reviewed studies with 50,000 total participants. The overall direction of effect is positive.

Outros ingredientes para Coronary Artery Disease (CAD)

Folate (Vitamin B9) C Magnesium C Selenium C

Omega-3 Fatty Acids (EPA/DHA) para outras condições

High Triglycerides (Hypertriglyceridemia) A Cardiac Arrhythmia B

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        Aviso Legal da FDA:
        Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.