Resveratrol pour High Blood Pressure (Hypertension)
B Preuves Au moins un essai randomisé le soutient, avec des résultats globalement concordants.Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.
En conclusion
Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.
Key Study Findings
Population: review of nutrition and lifestyle interventions for dyslipidemia and cardiometabolic risk
Population: review of age-related cardiac dysfunction and heart failure mechanisms
Population: Pregnant women with low calcium intake
Population: Menopausal women
Population: Mice with induced hypertension CA model
Population: Obese adults
Key Statistics
10
Études
600
Participants
Positive
Note
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Posologies couramment utilisées
- general:
- 150-500 mg/day
- cardiovascularsupport:
- 250-500 mg/day trans-resveratrol
Limite supérieure : Not formally established; GI discomfort common above 1,000 mg/day
Posologies étudiées dans la recherche
| Posologie | Durée | Effet | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| 500 mg daily | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| 75 mg | 14 weeks | Positive | 129 |
| None | -- | Mixed | -- |
Moment optimal de prise : With meals; bioavailability enhanced by piperine co-supplementation
Safety & Side Effects
Effets indésirables signalés
- ⚠ Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
- ⚠ Headache
- ⚠ May have estrogenic activity at high doses
Interactions connues
- ● Anticoagulants (may inhibit platelet aggregation)
- ● CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
- ● Blood pressure medications (additive hypotensive effect)
- ● Estrogen-sensitive conditions (weak estrogenic activity)
Apport maximal tolérable : Not formally established; GI discomfort common above 1,000 mg/day
Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.
Frequently Asked Questions
Does Resveratrol help with High Blood Pressure (Hypertension)?
How much Resveratrol should I take for High Blood Pressure (Hypertension)?
Are there side effects of Resveratrol?
How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?
Related Evidence
Autres ingrédients pour High Blood Pressure (Hypertension)
Resveratrol pour d'autres pathologies
References
- [1] Zhuyubing Fang et al.. ESC Heart Fail. 2025. Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. doi:10.1002/ehf2.14947 PubMed
- [2] Hygerta Berisha et al.. Nutrients. 2025. Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. doi:10.3390/nu17050776 PubMed
- [3] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
- [4] Ali Amini et al.. Cardiovasc Hematol Disord Drug Targets. 2025. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. doi:10.2174/011871529X398468250910225946 PubMed
- [5] Tao Jin et al.. Acta Biochim Pol. 2022. Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. doi:10.18388/abp.2020_5982 PubMed
- [6] Laura M Mongioì et al.. Int J Mol Sci. 2021. The Role of Resveratrol Administration in Human Obesity. doi:10.3390/ijms22094362 PubMed
- [7] Jay Jay Thaung Zaw et al.. Nutrients. 2020. Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. doi:10.3390/nu12030828 PubMed
- [8] Raúl Francisco Pastor et al.. Nutrients. 2020. Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. doi:10.3390/nu12103149 PubMed
- [9] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
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