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Resveratrol pour High Blood Pressure (Hypertension)

B Preuves Au moins un essai randomisé le soutient, avec des résultats globalement concordants.

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

B

En conclusion

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Effet: ~50% risk reduction

Population: Pregnant women with low calcium intake

Randomized Controlled Trial n=129 14 weeks
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women.
Dose: 75 mg vs: Placebo P < 0.001

Population: Older adults at risk of cognitive decline

Key Statistics

10

Études

600

Participants

↑

Positive

B

Note

Referenced Papers

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. Review
ESC heart failure 2025 58 citations
Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. Review
Nutrients 2025 32 citations
Dietary supplements and prevention of preeclampsia. Review
Hypertension research : … 2025 10 citations
The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. Other
Cardiovascular & hematological … 2025
Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. Other
Acta biochimica Polonica 2022 10 citations
The Role of Resveratrol Administration in Human Obesity. Review
International journal of … 2021 50 citations
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. Other
Nutrients 2020 49 citations
Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. Other
Nutrients 2020 16 citations
Nutritional prevention of cognitive decline and dementia. Review
Acta bio-medica : … 2018 103 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
150-500 mg/day
cardiovascularsupport:
250-500 mg/day trans-resveratrol

Limite supérieure : Not formally established; GI discomfort common above 1,000 mg/day

Posologies étudiées dans la recherche

Posologie Durée Effet N
500 mg daily -- Positive --
75 mg 14 weeks Positive 129

Moment optimal de prise : With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

Effets indésirables signalés

  • ⚠ Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
  • ⚠ Headache
  • ⚠ May have estrogenic activity at high doses

Interactions connues

  • ● Anticoagulants (may inhibit platelet aggregation)
  • ● CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
  • ● Blood pressure medications (additive hypotensive effect)
  • ● Estrogen-sensitive conditions (weak estrogenic activity)

Apport maximal tolérable : Not formally established; GI discomfort common above 1,000 mg/day

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Resveratrol help with High Blood Pressure (Hypertension)?
Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Resveratrol should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Resveratrol pour d'autres pathologies

Atherosclerosis C

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References

  
    
    
    
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      Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.
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      PubMed
    
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      Takafumi Ushida et al..
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      PubMed
    
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      Ali Amini et al..
      Cardiovasc Hematol Disord Drug Targets.
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      The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.
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      PubMed
    
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      PubMed
    
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      Jay Jay Thaung Zaw et al..
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      PubMed
    
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      [8]
      Raúl Francisco Pastor et al..
      Nutrients.
      2020.
      Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome.
      doi:10.3390/nu12103149
      PubMed
    
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        Avertissement FDA:
        Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.