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Astaxanthin ： High Cholesterol (Hyperlipidemia)

C エビデンス 小規模研究からのエビデンスは限られていますが、いくつかの肯定的なシグナルがあります。

Research suggests reductions in LDL and ox-LDL with improved blood rheology. Potent antioxidant but cardiovascular-specific trials are still small.

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            C

        

        

            
結論

            
            
Research suggests reductions in LDL and ox-LDL with improved blood rheology. Potent antioxidant but cardiovascular-specific trials are still small.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Other
                
                
                
                
            

            
                Antarctic Krill Euphausia superba Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced …
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Oxidative stress markers
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: Mouse model

            
        

        
        

            

                
                    Other
                
                
                
                
            

            
                Extensive Bioactivity of Astaxanthin from Haematococcus pluvialis in Human.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                効果: None
                
                
                None
                
            

            
            
対象集団: None

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
5

        
研究数

    

    

        
300

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
グレード

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Antarctic Krill Euphausia superba Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2024
                        
                        5 件の引用
                        
                    

                

                
                

                    

                        
                            Extensive Bioactivity of Astaxanthin from Haematococcus pluvialis in Human.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Advances in experimental …
                        2021
                        
                        13 件の引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
4-12 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
8-12 mg/day

                    

                    
                

                
                

                    上限量： Not formally established; up to 40 mg/day used in short-term studies
                

                
            

            

            
            

                
研究で検討された用量

                

                    

                        
                            

                                用量
                                期間
                                効果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                推奨摂取タイミング： With meals containing fat (carotenoid — fat-soluble)
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Orange skin discoloration at very high doses (harmless)
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Blood pressure medications (may have mild additive hypotensive effect)
                        
    • 
                        
                        
  • 
                            ●
                            Hormone-sensitive conditions (theoretical, as carotenoid)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Not formally established; up to 40 mg/day used in short-term studies
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Astaxanthin help with High Cholesterol (Hyperlipidemia)?
            
        
        

            Based on 5 studies with 300 participants, there is limited but promising evidence that Astaxanthin may support High Cholesterol (Hyperlipidemia) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Astaxanthin should I take for High Cholesterol (Hyperlipidemia)?
            
        
        

            Studies have used various dosages. A commonly studied range is 4-12 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Astaxanthin?
            
        
        

            Reported side effects may include Generally well-tolerated, Orange skin discoloration at very high doses (harmless), Mild gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Astaxanthin and High Cholesterol (Hyperlipidemia)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Astaxanthin 他の症状・状態について

                    

                        
                        
                            Endothelial Dysfunction
                            D

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Jun-Hui Choi et al..
      Nutrients.
      2024.
      Antarctic Krill Euphausia superba Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
      doi:10.3390/nu16213614
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Eiji Yamashita.
      Adv Exp Med Biol.
      2021.
      Extensive Bioactivity of Astaxanthin from Haematococcus pluvialis in Human.
      doi:10.1007/978-981-15-7360-6_23
      PubMed
    
    3. 
    
  















    

        FDAに関する免責事項:
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