Flaxseed Oil
fatty_acidAlso known as: Linseed Oil, ALA, Alpha-Linolenic Acid, Flax Oil
About
Flaxseed oil is a rich source of alpha-linolenic acid (ALA), a plant-based omega-3 that is partially converted to EPA (5-10%) and DHA (<5%). A 2015 meta-analysis of 11 RCTs found flaxseed supplementation significantly reduced both systolic (-2.85 mmHg) and diastolic (-2.39 mmHg) blood pressure, with greater effects in trials lasting >12 weeks.
How It Works
Rich source of alpha-linolenic acid (ALA), a plant-based omega-3 partially converted to EPA (5-10%) and DHA (<5%); lignans in ground flaxseed provide antioxidant and phytoestrogenic effects; ALA competes with omega-6 for COX/LOX enzymes reducing pro-inflammatory eicosanoid production; soluble fiber component supports healthy cholesterol metabolism.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| High Blood Pressure (Hypertension) | B | 11 | 700 | View → |
| Atherosclerosis | D | 2 | 150 | View → |
Side Effects
- Mild gastrointestinal discomfort (bloating, gas)
- Diarrhea at high doses
- Potential interaction with blood-thinning medications
Drug & Supplement Interactions
- Anticoagulants (mild additive antiplatelet effect)
- Blood pressure medications (additive hypotensive effect)
- May reduce absorption of oral medications if taken concurrently (fiber content)
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.