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Taurine için Heart Failure

C Kanıt Küçük çalışmalardan sınırlı kanıt mevcuttur, ancak bazı olumlu sinyaller bulunmaktadır.

Small RCTs show improved exercise capacity and cardiac function. Mechanistically compelling as the most abundant free amino acid in the heart. Larger trials are needed.

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Sonuç

            
            
Small RCTs show improved exercise capacity and cardiac function. Mechanistically compelling as the most abundant free amino acid in the heart. Larger trials are needed.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Other
                
                
                n=25
                
                
                4 weeks
                
                
            

            
                Effect of probiotic administration of Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 …
            
            

                
                Dose: Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917
                
                
                vs: phosphate-buffered saline (PBS)
                
                
                Outcome: visceral hypersensitivity (abdominal withdrawal reflex scores)
                
                
                Etki: None
                
                
                p<0.05
                
            

            
            
Popülasyon: female rats with water avoidance stress-induced IBS-D model

            
        

        
        

            

                
                    Controlled Clinical Trial
                
                
                
                6 weeks
                
                
            

            
                Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac …
            
            

                
                Dose: 400 mg/kg/day
                
                
                vs: ROFA exposure without taurine
                
                
                Outcome: Multi-organ oxidative stress and neuroinflammation
                
                
                Etki: None
                
                
                None
                
            

            
            
Popülasyon: Male Wistar rats with intranasal ROFA exposure

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Natural sulfur compounds in mental health and neurological disorders: insights from observational and intervention studies.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                Etki: None
                
                
                None
                
            

            
            
Popülasyon: None

            
        

        
        

            

                
                    Other
                
                
                
                
            

            
                Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine …
            
            

                
                Dose: 50 mg/kg lycopene in mice
                
                
                vs: HFD control mice
                
                
                Outcome: Cognitive function (Y-maze, MWM, novel object recognition)
                
                
                Etki: None
                
                
                None
                
            

            
            
Popülasyon: HFD-induced obese male C57BL/6 mice

            
        

        
        

            

                
                    Other
                
                
                
                
            

            
                Transcriptomics study of hippocampus in mice exposed to heat stress.
            
            

                
                Dose: None
                
                
                vs: Heat stress without taurine
                
                
                Outcome: Hippocampal gene expression and cognitive function
                
                
                Etki: None
                
                
                None
                
            

            
            
Popülasyon: Mice exposed to heat stress

            
        

        
        

            

                
                    Other
                
                
                
                
            

            
                Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                Etki: None
                
                
                p < .05
                
            

            
            
Popülasyon: Insomnia patients

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
4

        
Çalışmalar

    

    

        
200

        
Katılımcılar

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Derece

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Effect of probiotic administration of Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 on metabolic profiles in an …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Journal of the …
                        2026
                        
                    

                

                
                

                    

                        
                            Natural sulfur compounds in mental health and neurological disorders: insights from observational and intervention studies.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Frontiers in nutrition
                        2025
                        
                        7 atıf
                        
                    

                

                
                

                    

                        
                            Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Clinical nutrition (Edinburgh, …
                        2025
                        
                        1 atıf
                        
                    

                

                
                

                    

                        
                            Transcriptomics study of hippocampus in mice exposed to heat stress.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Psychoneuroendocrinology
                        2025
                        
                        1 atıf
                        
                    

                

                
                

                    

                        
                            Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac tissues and promotes neuroinflammation, with …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Neurotoxicology
                        2025
                        
                    

                

                
                

                    

                        
                            Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        PloS one
                        2024
                        
                        5 atıf
                        
                    

                

                
                

                    

                        
                            Neuroinflammatory and Neurometabolomic Consequences From Inhaled Wildfire Smoke-Derived Particulate Matter in the Western United States.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Toxicological sciences : …
                        2022
                        
                        29 atıf
                        
                    

                

                
                

                    

                        
                            Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Journal of proteome …
                        2006
                        
                        80 atıf
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Yaygın Kullanılan Dozajlar

                

                    
                    

                        
general:

                        
1,000-3,000 mg/day

                    

                    
                    

                        
heartfailuresupport:

                        
2,000-3,000 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
1,500-3,000 mg/day

                    

                    
                

                
                

                    Üst sınır: EFSA considers 6,000 mg/day safe; up to 6,000 mg/day used in clinical trials
                

                
            

            

            
            

                
Araştırmalarda İncelenen Dozajlar

                

                    

                        
                            

                                Dozaj
                                Süre
                                Etki
                                N
                            

                        
                        
                            
                            

                                Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917
                                4 weeks
                                
                                    
                                    Positive
                                    
                                
                                25
                            

                            
                            

                                400 mg/kg/day
                                6 weeks
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                50 mg/kg lycopene in mice
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Negative
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                En iyi alım zamanı: Can be taken with or without food; divide doses >2,000 mg
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Bildirilen Yan Etkiler

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated even at high doses
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Drowsiness (mild, at high doses)
                        
    • 
                        
                    

                

                

                
                

                    
Bilinen Etkileşimler

                    
    
                        
                        
  • 
                            ●
                            Antihypertensives (additive blood pressure lowering)
                        
    • 
                        
                        
  • 
                            ●
                            Lithium (may alter lithium excretion)
                        
    • 
                        
                        
  • 
                            ●
                            Antiepileptic drugs (may modulate GABA activity)
                        
    • 
                        
                    

                

                

                
                

                    

                        Tolere edilebilir üst alım: EFSA considers 6,000 mg/day safe; up to 6,000 mg/day used in clinical trials
                    

                

                
            

            

                Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Taurine help with Heart Failure?
            
        
        

            Based on 4 studies with 200 participants, there is limited but promising evidence that Taurine may support Heart Failure management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Taurine should I take for Heart Failure?
            
        
        

            Studies have used various dosages. A commonly studied range is 1,000-3,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Taurine?
            
        
        

            Reported side effects may include Generally well-tolerated even at high doses, Mild gastrointestinal discomfort (rare), Drowsiness (mild, at high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Taurine and Heart Failure?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Taurine diğer sağlık durumları için

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Nazila Dardmeh et al..
      J Sci Food Agric.
      2026.
      Effect of probiotic administration of Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 on metabolic profiles in an …
      doi:10.1002/jsfa.70190
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Apeksha Rana et al..
      Front Nutr.
      2025.
      Natural sulfur compounds in mental health and neurological disorders: insights from observational and intervention studies.
      doi:10.3389/fnut.2025.1534000
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Yuqing Wu et al..
      Clin Nutr.
      2025.
      Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway.
      doi:10.1016/j.clnu.2025.06.005
      PubMed
    
    4. 
    
    
  4. 
      [4]
      Bin Li et al..
      Psychoneuroendocrinology.
      2025.
      Transcriptomics study of hippocampus in mice exposed to heat stress.
      doi:10.1016/j.psyneuen.2025.107279
      PubMed
    
    5. 
    
    
  5. 
      [5]
      Gedaias Noronha da Silva et al..
      Neurotoxicology.
      2025.
      Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac tissues and promotes neuroinflammation, with …
      doi:10.1016/j.neuro.2025.103347
      PubMed
    
    6. 
    
    
  6. 
      [6]
      Williams Kobik et al..
      PLoS One.
      2024.
      Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors.
      doi:10.1371/journal.pone.0289391
      PubMed
    
    7. 
    
    
  7. 
      [7]
      David Scieszka et al..
      Toxicol Sci.
      2022.
      Neuroinflammatory and Neurometabolomic Consequences From Inhaled Wildfire Smoke-Derived Particulate Matter in the Western United States.
      doi:10.1093/toxsci/kfab147
      PubMed
    
    8. 
    
    
  8. 
      [8]
      Francois-Pierre J Martin et al..
      J Proteome Res.
      2006.
      Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation.
      doi:10.1021/pr060157b
      PubMed
    
    9. 
    
  















    

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