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Cocoa Flavanols için High Blood Pressure (Hypertension)

C

Cochrane review: systolic -2.8 mmHg. Modest but consistent. COSMOS trial dose (500 mg/day) showed cardiovascular mortality benefit as secondary endpoint.

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C

Sonuç

Cochrane review: systolic -2.8 mmHg. Modest but consistent. COSMOS trial dose (500 mg/day) showed cardiovascular mortality benefit as secondary endpoint.

Key Statistics

20

Çalışmalar

1000

Katılımcılar

Positive

C

Derece

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Yaygın Kullanılan Dozajlar

general:
200-900 mg/day cocoa flavanols
darkchocolate:
30-40g/day (70%+ cacao)
cosmostrialdose:
500 mg/day

Üst sınır: Not formally established; 2,000 mg/day used in some trials

En iyi alım zamanı: With or without food; daily consumption for sustained vascular benefit

Safety & Side Effects

Bildirilen Yan Etkiler

  • Mild gastrointestinal discomfort
  • Caffeine-related effects (insomnia, nervousness — from cocoa/chocolate sources)
  • Headache (rare)
  • Weight gain (if consuming as chocolate rather than extract)

Bilinen Etkileşimler

  • Anticoagulants (mild antiplatelet effect at high doses)
  • MAO inhibitors (cocoa contains tyramine)
  • Adenosine (caffeine in cocoa may antagonize)
  • Blood pressure medications (additive hypotensive effect)

Tolere edilebilir üst alım: Not formally established; 2,000 mg/day used in some trials

Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.

Frequently Asked Questions

Does Cocoa Flavanols help with High Blood Pressure (Hypertension)?
Based on 20 studies with 1,000 participants, there is limited but promising evidence that Cocoa Flavanols may support High Blood Pressure (Hypertension) management. Our evidence grade is C (Some Evidence).
How much Cocoa Flavanols should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 200-900 mg/day cocoa flavanols. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Cocoa Flavanols?
Reported side effects may include Mild gastrointestinal discomfort, Caffeine-related effects (insomnia, nervousness — from cocoa/chocolate sources), Headache (rare), Weight gain (if consuming as chocolate rather than extract). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Cocoa Flavanols and High Blood Pressure (Hypertension)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 20 peer-reviewed studies with 1,000 total participants. The overall direction of effect is positive.

Related Evidence

Şu durum için diğer içerikler: High Blood Pressure (Hypertension)

Cocoa Flavanols diğer sağlık durumları için

FDA Sorumluluk Reddi: Bu ifadeler Gıda ve İlaç Dairesi (FDA) tarafından değerlendirilmemiştir. Bu web sitesindeki ürünler ve bilgiler herhangi bir hastalığı teşhis etmek, tedavi etmek, iyileştirmek veya önlemek amacıyla tasarlanmamıştır. Sunulan kanıt dereceleri, yayımlanmış hakemli araştırmalarımızın analizine dayanmaktadır ve tıbbi tavsiye niteliği taşımamaktadır. Herhangi bir takviye rejimine başlamadan önce her zaman sağlık uzmanınıza danışın.