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Niacin (Vitamin B3) для High Triglycerides (Hypertriglyceridemia)

B

Reduces triglycerides 20-50% dose-dependently. Particularly effective for combined dyslipidemia (high TG + low HDL). Flushing limits adherence with immediate-release forms.

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B

Итог

Reduces triglycerides 20-50% dose-dependently. Particularly effective for combined dyslipidemia (high TG + low HDL). Flushing limits adherence with immediate-release forms.

Key Statistics

8

Исследования

4000

Участники

Positive

B

Оценка

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

generalnutrition:
14-16 mg/day
lipidmodification:
1,000-2,000 mg/day (start at 500 mg/day and titrate)

Верхний предел: 35 mg/day for non-prescription use; prescription doses up to 3,000 mg/day under medical supervi

Лучшее время приёма: With dinner or at bedtime with a low-fat snack; aspirin 30 min before may reduce flushing

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Flushing (redness, warmth, itching — most common, especially immediate-release)
  • Gastrointestinal discomfort (nausea, diarrhea)
  • Hepatotoxicity (especially extended-release at high doses)
  • Hyperglycemia (may worsen blood sugar control)
  • Hyperuricemia (may precipitate gout)

Известные взаимодействия

  • Statins (increased risk of myopathy/rhabdomyolysis)
  • Blood pressure medications (additive hypotensive effect)
  • Diabetes medications (may counteract blood sugar control)
  • Anticoagulants (may increase bleeding risk)
  • Alcohol (may worsen flushing and hepatotoxicity)

Допустимый верхний уровень потребления: 35 mg/day for non-prescription use; prescription doses up to 3,000 mg/day under medical supervi

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Niacin (Vitamin B3) help with High Triglycerides (Hypertriglyceridemia)?
Based on 8 studies with 4,000 participants, there is moderate evidence from clinical studies that Niacin (Vitamin B3) may support High Triglycerides (Hypertriglyceridemia) management. Our evidence grade is B (Good Evidence).
How much Niacin (Vitamin B3) should I take for High Triglycerides (Hypertriglyceridemia)?
Studies have used various dosages. A commonly studied range is 14-16 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Niacin (Vitamin B3)?
Reported side effects may include Flushing (redness, warmth, itching — most common, especially immediate-release), Gastrointestinal discomfort (nausea, diarrhea), Hepatotoxicity (especially extended-release at high doses), Hyperglycemia (may worsen blood sugar control). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Niacin (Vitamin B3) and High Triglycerides (Hypertriglyceridemia)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 8 peer-reviewed studies with 4,000 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для High Triglycerides (Hypertriglyceridemia)

Niacin (Vitamin B3) для других состояний

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.