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Niacin (Vitamin B3) для High Triglycerides (Hypertriglyceridemia)

B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.

Reduces triglycerides 20-50% dose-dependently. Particularly effective for combined dyslipidemia (high TG + low HDL). Flushing limits adherence with immediate-release forms.

B

Итог

Reduces triglycerides 20-50% dose-dependently. Particularly effective for combined dyslipidemia (high TG + low HDL). Flushing limits adherence with immediate-release forms.

Key Study Findings

Randomized Controlled Trial 12 weeks
Efficacy of AI-Guided (GenAISTM) Dietary Supplement Prescriptions versus Traditional Methods for Lowering LDL Cholesterol: A …
Dose: 190 mg/d Outcome: Cholesterol levels p < 0.01

Популяция: Aged individuals

In Vitro
Immediate-release niacin and a monounsaturated fatty acid-rich meal on postprandial inflammation and monocyte characteristics in …
Dose: 2 g Outcome: inflammation markers

Популяция: Healthy volunteers

Key Statistics

8

Исследования

4000

Участники

↑

Positive

B

Оценка

Referenced Papers

Efficacy of AI-Guided (GenAISTM) Dietary Supplement Prescriptions versus Traditional Methods for Lowering LDL Cholesterol: A Randomized Parallel-Group Pilot Study. RCT
Nutrients 2024 5 цитирований
Immediate-release niacin and a monounsaturated fatty acid-rich meal on postprandial inflammation and monocyte characteristics in men with metabolic syndrome. Other
Clinical nutrition (Edinburgh, … 2023 11 цитирований
Hypertriglyceridemia. Other
The New England … 2008

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

generalnutrition:
14-16 mg/day
lipidmodification:
1,000-2,000 mg/day (start at 500 mg/day and titrate)

Верхний предел: 35 mg/day for non-prescription use; prescription doses up to 3,000 mg/day under medical supervi

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
190 mg/d 12 weeks Mixed --
2 g -- Mixed --

Лучшее время приёма: With dinner or at bedtime with a low-fat snack; aspirin 30 min before may reduce flushing

Safety & Side Effects

Зарегистрированные побочные эффекты

  • ⚠ Flushing (redness, warmth, itching — most common, especially immediate-release)
  • ⚠ Gastrointestinal discomfort (nausea, diarrhea)
  • ⚠ Hepatotoxicity (especially extended-release at high doses)
  • ⚠ Hyperglycemia (may worsen blood sugar control)
  • ⚠ Hyperuricemia (may precipitate gout)

Известные взаимодействия

  • ● Statins (increased risk of myopathy/rhabdomyolysis)
  • ● Blood pressure medications (additive hypotensive effect)
  • ● Diabetes medications (may counteract blood sugar control)
  • ● Anticoagulants (may increase bleeding risk)
  • ● Alcohol (may worsen flushing and hepatotoxicity)

Допустимый верхний уровень потребления: 35 mg/day for non-prescription use; prescription doses up to 3,000 mg/day under medical supervi

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Niacin (Vitamin B3) help with High Triglycerides (Hypertriglyceridemia)?
Based on 8 studies with 4,000 participants, there is moderate evidence from clinical studies that Niacin (Vitamin B3) may support High Triglycerides (Hypertriglyceridemia) management. Our evidence grade is B (Good Evidence).
How much Niacin (Vitamin B3) should I take for High Triglycerides (Hypertriglyceridemia)?
Studies have used various dosages. A commonly studied range is 14-16 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Niacin (Vitamin B3)?
Reported side effects may include Flushing (redness, warmth, itching — most common, especially immediate-release), Gastrointestinal discomfort (nausea, diarrhea), Hepatotoxicity (especially extended-release at high doses), Hyperglycemia (may worsen blood sugar control). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Niacin (Vitamin B3) and High Triglycerides (Hypertriglyceridemia)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 8 peer-reviewed studies with 4,000 total participants. The overall direction of effect is positive.

Другие ингредиенты для High Triglycerides (Hypertriglyceridemia)

Omega-3 Fatty Acids (EPA/DHA) A Omega-7 (Palmitoleic Acid) C Chitosan D

Niacin (Vitamin B3) для других состояний

High Cholesterol (Hyperlipidemia) B

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References

  
    
    
    
  1. 
      [1]
      Evgeny Pokushalov et al..
      Nutrients.
      2024.
      Efficacy of AI-Guided (GenAISTM) Dietary Supplement Prescriptions versus Traditional Methods for Lowering LDL Cholesterol: A Randomized Parallel-Group Pilot Study.
      doi:10.3390/nu16132023
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Sergio Montserrat-de la Paz et al..
      Clin Nutr.
      2023.
      Immediate-release niacin and a monounsaturated fatty acid-rich meal on postprandial inflammation and monocyte characteristics in men with metabolic syndrome.
      doi:10.1016/j.clnu.2023.08.017
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Robert Oh.
      N Engl J Med.
      2008.
      Hypertriglyceridemia.
      doi:10.1056/NEJMc072844
      PubMed
    
    4. 
    
  















    

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