What is the recommended dosage for Red Yeast Rice?

General: 1,200-2,400 mg/day providing 10 mg monacolin K; Lipid Support: 600 mg BID

What are the side effects of Red Yeast Rice?

Potential side effects include: Myalgia (muscle pain — same mechanism as statins), Gastrointestinal discomfort, Elevated liver enzymes (rare), Citrinin contamination risk in poorly manufactured products, Rhabdomyolysis (rare, at high doses).

What is red yeast rice and how may it support cardiovascular health?

Red yeast rice is fermented rice containing monacolin K, which is chemically identical to lovastatin. It has consistent clinical evidence for lowering LDL cholesterol. The CCSPS trial of 4,870 Chinese patients demonstrated significant reductions in cardiovascular events. However, monacolin K content varies greatly between products.

What dosage of red yeast rice has been studied for cholesterol reduction?

Clinical trials used red yeast rice preparations providing 2.4–10 mg of monacolin K per day. EU regulations limit supplements to products providing less than 3 mg monacolin K daily, while the FDA considers higher amounts as unapproved drugs. Product consistency and citrinin contamination are significant quality concerns.

What are the potential side effects of red yeast rice?

Because monacolin K is identical to lovastatin, red yeast rice carries the same risk of side effects: myopathy, rhabdomyolysis, and liver damage. Some products contain citrinin, a nephrotoxic mycotoxin. Red yeast rice may interact with drugs that interact with statins. CoQ10 depletion is possible, as with all statin-like compounds.

Red Yeast Rice
Red Yeast Rice

herb

Também conhecido como: Monascus purpureus, Monacolin K, Xuezhikang, Hong Qu, Cholestin

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Red yeast rice contains monacolin K, chemically identical to lovastatin, which inhibits HMG-CoA reductase. The CCSPS trial (4,870 post-MI patients) demonstrated Xuezhikang reduced recurrent MI by 45% and total mortality by 33%. However, the FDA has taken enforcement action against high-monacolin K products, and product quality varies enormously — citrinin contamination is a significant concern.

How It Works

Contains monacolin K — chemically identical to lovastatin — which inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis; additional monacolins and phytosterols may provide cholesterol-lowering effects beyond monacolin K alone; isoflavones and sterols provide antioxidant and anti-inflammatory properties.

Evidence For Conditions

Condição	Nota	Estudos	Participantes
High Cholesterol (Hyperlipidemia)	A	22	8000	Ver →

Side Effects

Myalgia (muscle pain — same mechanism as statins)
Gastrointestinal discomfort
Elevated liver enzymes (rare)
Citrinin contamination risk in poorly manufactured products
Rhabdomyolysis (rare, at high doses)

Drug & Supplement Interactions

Statins (contraindicated — same mechanism, additive myopathy risk)
CYP3A4 inhibitors (grapefruit juice, certain antibiotics — increased monacolin K levels)
Fibrates (increased myopathy risk)
Cyclosporine (increased myopathy risk)
Niacin (increased myopathy risk at high doses)

Informe sempre o seu profissional de saúde sobre todos os suplementos que você toma.Sempre informe seu profissional de saúde sobre todos os suplementos que você toma.

Related Ingredients

Hawthorn Garlic Curcumin Berberine

Dados Rápidos

Dosagem: General: 1,200-2,400 mg/day providing 10 mg monacolin K; Lipid_Support: 600 mg BID
Formas: capsule tablet
Fontes Naturais: Rice fermented with Monascus purpureus yeast
Limite Superior: EU-regulated maximum: 10 mg monacolin K/day; quality varies dramatically between products
Melhor Horário: With dinner (cholesterol synthesis peaks overnight)

Resumo das Evidências

High Cholesterol (Hyperlipidemia) A

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.