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HeartCited

Red Yeast Rice
Red Yeast Rice

herb

다른 이름: Monascus purpureus, Monacolin K, Xuezhikang, Hong Qu, Cholestin

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About





            

                
Red yeast rice contains monacolin K, chemically identical to lovastatin, which inhibits HMG-CoA reductase. The CCSPS trial (4,870 post-MI patients) demonstrated Xuezhikang reduced recurrent MI by 45% and total mortality by 33%. However, the FDA has taken enforcement action against high-monacolin K products, and product quality varies enormously — citrinin contamination is a significant concern.

            

        

        

        
        
        

            

  
How It Works





            

                
Contains monacolin K — chemically identical to lovastatin — which inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis; additional monacolins and phytosterols may provide cholesterol-lowering effects beyond monacolin K alone; isoflavones and sterols provide antioxidant and anti-inflammatory properties.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                건강 상태
                                등급
                                연구
                                참여자
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Cholesterol (Hyperlipidemia)
                                    
                                
                                
                                    A

                                
                                
                                    22
                                
                                
                                    8000
                                
                                
                                    
                                        보기 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Myalgia (muscle pain — same mechanism as statins)
                
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                    Gastrointestinal discomfort
                
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                    Elevated liver enzymes (rare)
                
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                    Citrinin contamination risk in poorly manufactured products
                
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                    Rhabdomyolysis (rare, at high doses)
                
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Drug & Supplement Interactions





            
    
                
                
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                    Statins (contraindicated — same mechanism, additive myopathy risk)
                
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                    CYP3A4 inhibitors (grapefruit juice, certain antibiotics — increased monacolin K levels)
                
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                    Fibrates (increased myopathy risk)
                
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                    Cyclosporine (increased myopathy risk)
                
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                    Niacin (increased myopathy risk at high doses)
                
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                복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Hawthorn
                    
                
                
                
                    Garlic
                    
                
                
                
                    Curcumin
                    
                
                
                
                    Berberine
                    
                
                
            

        

        
    


    
    












    

        FDA 면책 조항:
        이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.