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Omega-3 Fatty Acids (EPA/DHA)
Omega-3 Fatty Acids (EPA/DHA)

fatty_acid

別名: Fish Oil, Marine Omega-3, Eicosapentaenoic Acid, Docosahexaenoic Acid, EPA, DHA

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About





            

                
Omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are long-chain polyunsaturated fats from marine sources that support cardiovascular health through multiple mechanisms. EPA/DHA incorporate into cell membranes, modulate inflammatory signaling, lower plasma triglycerides, and improve endothelial function. The REDUCE-IT trial demonstrated that high-dose EPA (4g/day) reduced major adverse cardiovascular events by 25%.

            

        

        

        
        
        

            

  
How It Works





            

                
Long-chain polyunsaturated fatty acids that incorporate into cell membranes modulating inflammatory signaling via reduced arachidonic acid conversion to pro-inflammatory eicosanoids; lower plasma triglycerides by reducing hepatic VLDL production and increasing lipoprotein lipase activity; improve endothelial function by enhancing nitric oxide bioavailability; stabilize cardiac myocyte membranes reducing arrhythmia susceptibility through ion channel modulation.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                症状・状態
                                グレード
                                研究数
                                参加者数
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Triglycerides (Hypertriglyceridemia)
                                    
                                
                                
                                    A

                                
                                
                                    50
                                
                                
                                    20000
                                
                                
                                    
                                        詳細を見る →
                                    
                                
                            

                            
                            

                                
                                    
                                        Coronary Artery Disease (CAD)
                                    
                                
                                
                                    B

                                
                                
                                    20
                                
                                
                                    50000
                                
                                
                                    
                                        詳細を見る →
                                    
                                
                            

                            
                            

                                
                                    
                                        Cardiac Arrhythmia
                                    
                                
                                
                                    B

                                
                                
                                    15
                                
                                
                                    10000
                                
                                
                                    
                                        詳細を見る →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Fishy aftertaste or burping
                
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                    Mild gastrointestinal discomfort
                
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                    Potential increased bleeding time at very high doses
                
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                    May increase atrial fibrillation risk at doses >2g/day
                
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Drug & Supplement Interactions





            
    
                
                
  • 
                    
                    Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
                
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                    Blood pressure medications (additive hypotensive effect)
                
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                    Orlistat (may reduce omega-3 absorption)
                
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                服用しているすべてのサプリメントについて、必ず医療提供者にお知らせください。摂取しているすべてのサプリメントについて、必ず医療専門家にお知らせください。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Krill Oil
                    
                
                
                
                    Omega-7 (Palmitoleic Acid)
                    
                
                
                
                    Flaxseed Oil
                    
                
                
            

        

        
    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。