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Omega-7 (Palmitoleic Acid) for High Triglycerides (Hypertriglyceridemia)

C

Cleveland Clinic study: TG -15%, CRP -44%. Very limited data from a single prospective RCT. Larger confirmatory trials are needed.

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The Bottom Line

            
            
Cleveland Clinic study: TG -15%, CRP -44%. Very limited data from a single prospective RCT. Larger confirmatory trials are needed.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
2

        
Studies

    

    

        
100

        
Participants

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Grade

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Commonly Used Dosages

                

                    
                    

                        
general:

                        
210-420 mg/day purified palmitoleic acid

                    

                    
                

                
                

                    Upper limit: Not formally established
                

                
            

            

            

            
            

                Best taken: With meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Reported Side Effects

                    
    
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
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  • 
                            ⚠
                            May interact with blood-thinning medications at high doses
                        
    • 
                        
                    

                

                

                
                

                    
Known Interactions

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (theoretical additive effect)
                        
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                            ●
                            Lipid-lowering medications (may have additive effects)
                        
    • 
                        
                    

                

                

                
                

                    

                        Tolerable upper intake: Not formally established
                    

                

                
            

            

                Always consult your healthcare provider before starting any supplement.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Omega-7 (Palmitoleic Acid) help with High Triglycerides (Hypertriglyceridemia)?
            
        
        

            Based on 2 studies with 100 participants, there is limited but promising evidence that Omega-7 (Palmitoleic Acid) may support High Triglycerides (Hypertriglyceridemia) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Omega-7 (Palmitoleic Acid) should I take for High Triglycerides (Hypertriglyceridemia)?
            
        
        

            Studies have used various dosages. A commonly studied range is 210-420 mg/day purified palmitoleic acid. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Omega-7 (Palmitoleic Acid)?
            
        
        

            Reported side effects may include Mild gastrointestinal discomfort, May interact with blood-thinning medications at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Omega-7 (Palmitoleic Acid) and High Triglycerides (Hypertriglyceridemia)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Other ingredients for High Triglycerides (Hypertriglyceridemia)

                    

                        
                        
                            Omega-3 Fatty Acids (EPA/DHA)
                            A

                        
                        
                        
                            Niacin (Vitamin B3)
                            B

                        
                        
                        
                            Chitosan
                            D

                        
                        
                    

                

                

                
                

                    
Omega-7 (Palmitoleic Acid) for other conditions

                    

                        
                        
                            Atherosclerosis
                            D

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDA Disclaimer:
        These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.