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Red Yeast Rice
Red Yeast Rice

herb

يُعرف أيضاً بـ: Monascus purpureus, Monacolin K, Xuezhikang, Hong Qu, Cholestin

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About





            

                
Red yeast rice contains monacolin K, chemically identical to lovastatin, which inhibits HMG-CoA reductase. The CCSPS trial (4,870 post-MI patients) demonstrated Xuezhikang reduced recurrent MI by 45% and total mortality by 33%. However, the FDA has taken enforcement action against high-monacolin K products, and product quality varies enormously — citrinin contamination is a significant concern.

            

        

        

        
        
        

            

  
How It Works





            

                
Contains monacolin K — chemically identical to lovastatin — which inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis; additional monacolins and phytosterols may provide cholesterol-lowering effects beyond monacolin K alone; isoflavones and sterols provide antioxidant and anti-inflammatory properties.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                الحالة
                                التقييم
                                الدراسات
                                المشاركون
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Cholesterol (Hyperlipidemia)
                                    
                                
                                
                                    A

                                
                                
                                    22
                                
                                
                                    8000
                                
                                
                                    
                                        عرض →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Myalgia (muscle pain — same mechanism as statins)
                
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                    Gastrointestinal discomfort
                
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                    Elevated liver enzymes (rare)
                
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                    Citrinin contamination risk in poorly manufactured products
                
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                    Rhabdomyolysis (rare, at high doses)
                
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Drug & Supplement Interactions





            
    
                
                
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                    Statins (contraindicated — same mechanism, additive myopathy risk)
                
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                    CYP3A4 inhibitors (grapefruit juice, certain antibiotics — increased monacolin K levels)
                
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                    Fibrates (increased myopathy risk)
                
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                    Cyclosporine (increased myopathy risk)
                
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                    Niacin (increased myopathy risk at high doses)
                
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                أخبر مقدم الرعاية الصحية دائماً بجميع المكملات التي تتناولها.
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Hawthorn
                    
                
                
                
                    Garlic
                    
                
                
                
                    Curcumin
                    
                
                
                
                    Berberine
                    
                
                
            

        

        
    


    
    












    

        إخلاء مسؤولية FDA:
        لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.