What is the recommended dosage for Hawthorn?

General: 450-900 mg/day standardized extract (WS 1442 or LI 132); Standardization: 18.75% OPCs or 2.2% flavonoids

What are the side effects of Hawthorn?

Potential side effects include: Generally well-tolerated, Dizziness, Nausea, Gastrointestinal discomfort, Headache.

What is hawthorn and how may it support cardiovascular health?

Hawthorn (Crataegus) has been used for centuries in traditional medicine for heart conditions. It contains flavonoids and oligomeric proanthocyanidins that may improve coronary blood flow, increase cardiac contractility, and reduce blood pressure. Several European trials showed benefits for mild heart failure symptoms.

What dosage of hawthorn has been studied in cardiovascular trials?

Clinical studies have used 160–1,800 mg per day of hawthorn leaf and flower extract standardized to 2.2% flavonoids or 18.75% OPCs. The SPICE trial used WS 1442 extract at 900 mg daily for 24 months in heart failure patients. Lower doses of 160–480 mg daily are used for milder cardiovascular support.

What are the potential side effects of hawthorn?

Hawthorn is generally well tolerated. Mild side effects include dizziness, nausea, and digestive discomfort. It may enhance the effects of cardiac glycosides (digoxin), blood pressure medications, and vasodilators. Individuals taking heart medications should consult a cardiologist before using hawthorn.

Hawthorn
Hawthorn

herb

Также известен как: Crataegus, Crataegus monogyna, Crataegus laevigata, Hawthorne, Whitethorn

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About

Hawthorn berry/leaf/flower extract contains OPCs and flavonoids that improve cardiac contractile force without increasing oxygen demand. A 2008 Cochrane review of 14 RCTs (1,110 heart failure patients) found hawthorn significantly improved exercise tolerance and reduced dyspnea. Hawthorn is approved by the German Commission E for declining cardiac function (NYHA I-II).

How It Works

Oligomeric procyanidins and flavonoids inhibit phosphodiesterase-3 (PDE3) increasing cardiac cAMP and improving contractile force (positive inotropic effect without increasing oxygen demand); enhances coronary artery blood flow via endothelium-dependent vasodilation; reduces peripheral vascular resistance; antioxidant flavonoids protect against myocardial ischemia-reperfusion injury; mild ACE-inhibitory activity.

Evidence For Conditions

Состояние	Оценка	Исследования	Участники
Heart Failure	B	14	3800	Подробнее →
High Blood Pressure (Hypertension)	C	4	300	Подробнее →

Side Effects

Generally well-tolerated
Dizziness
Nausea
Gastrointestinal discomfort
Headache

Drug & Supplement Interactions

Cardiac glycosides (digoxin — may enhance inotropic effects)
Antihypertensives (additive blood pressure lowering)
Beta-blockers (additive cardiac effects)
PDE5 inhibitors (additive vasodilation)

Всегда сообщайте лечащему врачу обо всех принимаемых добавках.

Related Ingredients

Garlic Curcumin Berberine Red Yeast Rice

Основные факты

Дозировка: General: 450-900 mg/day standardized extract (WS 1442 or LI 132); Standardization: 18.75% OPCs or 2.2% flavonoids
Формы выпуска: capsule tablet liquid tincture dried berry tea
Природные источники: Hawthorn berries, leaves, and flowers (Crataegus species)
Верхний предел: Not formally established; up to 1,800 mg/day used in the SPICE trial
Лучшее время приёма: With meals; effects require 6-8 weeks of continuous use

Обзор доказательной базы

Heart Failure B

High Blood Pressure (Hypertension) C

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.